Results 91 to 100 of about 8,221 (217)

Aloe vera in Food Preservation: Harnessing Bioactive Constituents for Clean‐Label Innovation and Safety Assurance

open access: yesFood Safety and Health, EarlyView.
Aloe vera‐derived biopolymers and nanoformulations enhance antimicrobial, antioxidant, and barrier functions in clean‐label edible coatings and films, whereas safety‐critical anthraquinone thresholds and regulatory constraints shape their translational potential.
Acharya Balkrishna   +6 more
wiley   +1 more source

Isorhamnetin Alleviates Renal Fibrosis Induced by Renal Tubular Epithelial Cell Senescence Via Inhibition of the IL‐6/IL‐6R Signaling Pathway

open access: yesiMetaMed, EarlyView.
IL‐6 from RTECs upregulates TGF‐β in macrophages, promoting fibroblast transdifferentiation. Isorhamnetin inhibits this effect. ABSTRACT Chronic kidney disease (CKD) is a major global health issue. Kidney fibrosis is a key mechanism leading to end‐stage renal disease.
Weifei Liang   +8 more
wiley   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

open access: yesInterdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui   +12 more
wiley   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu   +6 more
wiley   +1 more source

Joint Angular Excursions and Angular Range Utilization During Stance‐Phase Locomotion in Terrestrial Mammals: A Comparative Morphofunctional Data Set

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
This study quantifies stance‐phase joint angular excursions and angular utilization (AUI%) during walking in 182 terrestrial mammal species. Across mammals, total limb excursion during stance (TAE) decreases with increasing body mass, whereas AUI% remains broadly conserved, indicating similar proportional use of summed joint excursions to generate net ...
Paul Medina‐González
wiley   +1 more source

The Art of Reception: Field Visits as Microcosms for Development Interventions of Non‐Governmental Organisations in Uganda

open access: yesJournal of International Development, EarlyView.
ABSTRACT Field visits are common phenomena with non‐governmental organisations in Uganda. During these visits, Ugandan national staff guide visitors on series of meetings and interactions in the field. Following an actor‐oriented approach and drawing on ethnographic data on 14 field visits, this paper understands the field visit as a microcosm for the ...
Caspar Edward Swinkels
wiley   +1 more source

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

open access: yesMovement Disorders, EarlyView.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step   +680 more
wiley   +1 more source

Marine trophic architecture and hidden ecological connections in the Strait of Magellan: keystone species and ecosystem resilience

open access: yesOikos, EarlyView.
Understanding the ecological implications of species coexistence is central to biodiversity studies and to identify environmental and anthropogenic drivers of ecosystem dynamics, where ecological network analysis offers valuable insights. This study examines the complexity, structure, and potential responses to disturbances of the Strait of Magellan's ...
Claudia D. Andrade   +4 more
wiley   +1 more source

Marine litter can shift sea turtle nests toward the shoreline

open access: yesOikos, EarlyView.
Marine litter is an emerging threat to sea turtle rookeries, yet its effects on nesting behaviour remain poorly understood. In this study, we investigated how macro‐litter accumulation on beaches influences the spatial distribution of loggerhead turtle Caretta caretta nests on Boa Vista Island, Cabo Verde.
Diana Sousa‐Guedes   +4 more
wiley   +1 more source

When Politics Shapes Administration: Bureaucratic Autonomy, Policy Role Separation, and Organizational Capacity in an Institutionally Weak Public Administration

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT This study examines the impact of administrative autonomy and the separation of roles in public policy on organizational capacity within hybrid public administration systems, particularly in Colombia. It explores the dynamics between elected officials and civil servants, focusing on how the division of responsibilities and the autonomy granted
Camilo Ignacio González   +1 more
wiley   +1 more source

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