Results 81 to 90 of about 2,747,906 (255)

Acto de reconocimiento "Con Chile y la Universidad en el corazón"

open access: yes, 2013
La U. de Chile rindió homenaje a los detenidos desaparecidos en dictadura, en emotivo y masivo acto realizado en Casa Central el 11 de septiembre de 2013, al cumplirse 40 años del Golpe ...
Universidad de Chile. Rectoría   +1 more
core  

Nuevo portal web de la Universidad de Chile [PDF]

open access: yes, 2010
Ponencia presentada en las "9as Jornadas Bibliotecarias de la U. de Chile: Bibliotecas en la web social... Hazte fan de los usuarios digitales", Santiago de Chile, 21 de enero del 2010, organizadas por el Sistema de Servicios de Información y Bibliotecas
Ortúzar Fontt, Gabriela
core  

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin   +17 more
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Chile 2003-2004: los nuevos escenarios (inter) nacionales [PDF]

open access: yes
Chile 2003-2004. Los nuevos escenarios internacionales es una mirada hacia el interior del país, bajo el entendido que Chile no está ajeno a los profundos cambios que suceden mas allá de sus fronteras.
FLACSO Chile
core   +1 more source

International cooperation between Chile and Haiti: the decentralization of cooperation on migratory issues [PDF]

open access: yes, 2020
Tesis para optar al grado de Magíster en Estudios Internacionales.Esta investigación tiene como objetivo general analizar las características de la cooperación internacional en temas migratorios entre Chile y Haití, partiendo de la hipótesis de que la ...
Joseph, Erica
core  

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

open access: yesAdvanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang   +14 more
wiley   +1 more source

Project Vicissitudes. Private ironism and critique of ideologies

open access: yesMateria Arquitectura, 2013
The virtual discredit of the modern notion of “project” as a rational achievement of an emancipatory political telos emerges as a counterface of the persistent reduction of the project exercise to the significant plan of representation resources, an ...
José Solís
doaj   +1 more source

Multi-source qualitative analysis of emergency medicine residency programmes in Chile: A case studyAnálisis cualitativo de múltiples fuentes de programas de residencia en Medicina de Urgencia en Chile: un estudio de caso

open access: yes
© 2023 The AuthorsBackground: Emergency medicine (EM) is a developing specialty worldwide. In Chile, it has been developing for 25 years, however, there is a need for further progress. Aim: We aimed to explore the current postgraduate curriculum in Chile
Basauri S., Scanlan G.M., Muir F.
core   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

open access: yesAdvanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang   +11 more
wiley   +1 more source

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