Results 61 to 70 of about 1,847,707 (215)

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

Materia y memoria: tesoros patrimoniales de la Universidad de Chile

, 2012
oai:omp.libros.uchile.cl:publicationFormat/2Este libro nos enfrenta a una mirada sobre la historia de la Universidad de Chile centrada en sus más preciados patrimonios.
Araya Espinoza, Alejandra Natalia; Universidad de Chile, Montecino Aguirre, Sonia   +1 more
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Advancing Fruit Bioimpedance Monitoring With Sustainable, Soft, And Bio‐Based Electrodes Beyond ECG

Advanced Electronic Materials, EarlyView.
Electrical impedance spectroscopy enables non‐destructive fruit quality monitoring, but conventional ECG and needle electrodes compromise signal stability, fruit physiology, and sustainability. This perspective highlights the transition toward soft, biocompatible, and biodegradable electrode interfaces based on natural substrates, bio‐derived ...
Sundus Riaz, Ahmed Rasheed, Angelo Zanella, Almudena Rivadeneyra, Paolo Lugli, Luisa Petti, Pietro Ibba   +6 more
wiley   +1 more source

Dimensions of the AI Divide: Digital Inequality and Psychological Consequences

AI &Innovation, EarlyView.
ABSTRACT Artificial intelligence (AI) has become a foundational component of contemporary social, economic, and political life. Yet, the ways in which AI reshapes patterns of exclusion beyond questions of access and technical capability remain insufficiently theorized.
Christos Papaioannou
wiley   +1 more source

Innovative Artificial Intelligence‐Assisted Systems for Social Science Research: Architecture Design and Applied Practice

AI &Innovation, EarlyView.
ABSTRACT The rapid advancement of large language model (LLM) technology is profoundly transforming the practice of social science research. Scholarly discussions on Artificial Intelligence (AI)'s role in social science research can be organised into three levels: AI as a research tool, AI as a methodological infrastructure and AI as a quasi‐cognitive ...
Jie Xiong
wiley   +1 more source

Chile 96: análisis y opiniones

Chile continuó creciendo en 1996. El Producto Interno Bruto (PIB) se incrementó en un 7,2%, completándose más de una década de crecimiento ininterrumpido y con una tasa promedio superior al 6,5% anual. La tasa de desocupación en 1996 fue de un 6,5%.
FLACSO Chile
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A Global Prospective Harmonization Framework for Suicidality, Anhedonia, and Obsessive‐Compulsive Symptoms in Psychiatric Genetic Studies: A Cross‐Continental Study Within the Ancestral Population Network

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT This study aims to prospectively collect harmonized, quantitative, and dimensional psychiatric phenotypes (suicidality, anhedonia, and obsessive‐compulsive symptoms) and information on discrimination, stigma, and unfair treatment in up to 27,500 individuals across diverse ancestries and clinical populations for genetic analysis within the NIMH
Ana M. Diaz‐Zuluaga, Jacey L. Anderberg, Ana M. Ramirez‐Diaz, Andrea Horvath Marques, Catherine E. Rast, Daniel Bustamante, Deborah Jonker, Johanna Valencia‐Echeverry, Joseph Kyebuzibwa, Josselyn S. Muñoz, Kristien van der Walt, Mauricio Castaño Ramirez, Olivia Wootton, Renee M. Frederick, Rocky E. Stroud II, Ruben Gur, Sang Jin Rhee, Shaili C. Jha, Stella Gichuru, Susan Service, Victor I. Reus, Akena Dickens, Carlos Lopez‐Jaramillo, Carrie E. Bearden, Dan J. Stein, Ezra S. Susser, James J. Crowley, Jonathan Flint, Kenneth S. Kendler, Lukoye Atwoli, Michele T. Pato, Nelson B. Freimer, Roel A. Ophoff, Yong Min Ahn, Loes Olde Loohuis, Eric A. Storch, Bizu Gelaye   +36 more
wiley   +1 more source

Actas del Primer Congreso Latinoamericano de Niñez y Políticas Públicas, Santiago de Chile, 14 al 17 de enero 2014:

, 2015
El I Congreso Latinoamericano sobre Niñez y Políticas Públicas. Balances, desafíos y compromisos para una nueva ciudadanía. Diálogos interdisciplinarios desde América Latina, realizado en Santiago de Chile entre el 14 y 17 de enero de 2014, en ...
Congreso Latinoamericano de Niñez y Políticas Públicas; Universidad de Chile
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Chile 97: análisis y opiniones

FLACSO, por medio de Chile 97. Análisis y opiniones, efectúa un aporte a la reflexión sobre el país en el marco latinoamericano. A través de las distintas secciones y capítulos se dan a conocer estudios, análisis y perspectivas sobre los principales ...
FLACSO Chile
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Debate ARCHI: elecciones presidenciales en Chile 2009

, 2009
Este viernes 9 de octubre, Polar Comunicaciones transmitirá en vivo todos los detalles del debate radial en que participarán los cuatro aspirantes a la Moneda.
Chile. Universidad Mayor
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