Results 81 to 90 of about 2,251,534 (260)

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

open access: yesAdvanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou   +14 more
wiley   +1 more source

La arquitectura moderna en la producción de la gran ciudad : Chile 1930-1970 [PDF]

open access: yes, 2013
En Chile la arquitectura moderna estuvo directamente asociada a la producción del fenómeno urbano durante el siglo xx, y dio forma a la ciudad incluso más allá del espacio construido, reflejando las condiciones de un nuevo estado de situación social y ...
Torrent Schneider, Horacio
core   +2 more sources

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

Casa Corralones Paine, Chile

open access: yesARQ, 2005
Cuidadosos y modestos remiendos dan lugar a diferentes situaciones espaciales, acomodadas en una bodega de adobe. La brutalidad de los nuevos elementos los deja velados y fundidos en el espacio gastado; esta lógica introvertida se manifiesta en una ...
Magdalena Bernstein, Mathias Klotz
doaj  

Addressing Water Scarcity in Isla Huichas, Chile: A Tecno-Economic Sustainable Solution

open access: yesWorld
Islas Huichas, located in Chile’s remote Aysén region, has long faced water scarcity due to a lack of natural sources. The community relies on rainwater collection pools managed by the Rural Drinking Water Committee (RDWC), which face increased pressure ...
Benjamín Borquez   +4 more
doaj   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

open access: yesAdvanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang   +7 more
wiley   +1 more source

The Lifestyles of Space Standards: Concepts and Design Problems

open access: yesUrban Planning
Space standards are envisioned as a powerful means to regulate dwelling design, ensuring the quality, functionality, and safety of homes. Their ultimate objective is to guarantee a minimum level of design quality that can accommodate a wide range of ...
Alvaro Arancibia
doaj   +1 more source

Architectural representation and project critique. New fields of meaning

open access: yesMateria Arquitectura, 2014
The paper introduces a discussion framework about the representation concept in architecture. This approach proposes that the validity of the representation strategies is based on its capacity to link the discursive field (theory) with the operating ...
Felipe Corvalán
doaj   +1 more source

The hidden biotic face of microbialite morphogenesis – a case study from Laguna de Los Cisnes, southernmost Patagonia (Chile)

open access: yesSedimentology
Microbialites provide geological evidence into Earth's early ecosystems, recording long‐standing interactions between co‐evolving life and the environment.
Clément Pollier   +3 more
semanticscholar   +1 more source

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

open access: yesAdvanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee   +6 more
wiley   +1 more source

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