Results 101 to 110 of about 2,747,378 (288)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

Materia y memoria: tesoros patrimoniales de la Universidad de Chile

, 2012
oai:omp.libros.uchile.cl:publicationFormat/2Este libro nos enfrenta a una mirada sobre la historia de la Universidad de Chile centrada en sus más preciados patrimonios.
Araya Espinoza, Alejandra Natalia; Universidad de Chile, Montecino Aguirre, Sonia   +1 more
core   +1 more source

Editorial: Recuperación patrimonial y estrategias de revitalización social

Arquitecturas del Sur, 2018
Este número 53 de Arquitecturas del Sur se centra en el tema de la arquitectura patrimonial con la intención de contribuir al debate en torno al proyecto de arquitectura y su asombroso potencial para iniciar procesos de recuperación significativa en la ...
Hernán Ascui Fernández
doaj  

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

Seguridad urbana en tensión: desafíos estructurales del urbanismo latinoamericano

Urbano
En las últimas décadas, la seguridad urbana se ha convertido en uno de los temas más urgentes y complejos del debate sobre la ciudad en América Latina.
Stella Schröder
doaj   +1 more source

Polyelectrolyte Multilayer: Caged PTFE Particles in Water for Continuous, Sonochemical H2O2 Synthesis

Advanced Science, EarlyView.
A yolk–shell PTFE‐based composite (YSP) enables tunable, robust hydrophobic–water interfaces for efficient, on‐demand sonocatalytic H2O2 generation and pollutant degradation. ABSTRACT The use of polytetrafluoroethylene (PTFE) particles to promote sonochemical H2O2 production has attracted growing interest, as cavitation bubbles formed at or near their ...
Rong Wang, Bo Wang, Tengyue Fu, Yue Yang, Chongling Cheng, Zhenhui Qi, Dayang Wang   +6 more
wiley   +1 more source

Bio‐Inspired Oligocellulose‐Regulated Ice‐Water Interfaces Enable Sustained Ion Transport in Frozen Aqueous Zinc Batteries

Advanced Science, EarlyView.
Inspired by antifreeze glycoproteins (AFGPs), we synthesized a type of oligomeric cellulose (OC‐8) to inhibit ice formation and enlarge the inter‐ice water channel for transportation. Typical confocal fluorescence experiments display the expansion of the ice‐water interface for zinc‐ion transport.
Zeyu Zhu, Jingxuan Pan, Haoran Ma, Boya Yuan, Cristina Carucci, Sunghak Park, Chong Gao, Minmin Liang, Kaiqi Li, Wei Li, Dan Wang, Xiaoting Chen, Zhiyuan He   +12 more
wiley   +1 more source

Enviromics and Abiotic Enviromics: Enhancing Stress Biology and Plant Resilience Breeding

Advanced Science, EarlyView.
Environmental stressors are captured through high‐throughput envirotyping and integrated into an enviromic framework with genomic, transcriptomic, phenomic, and environmental data. AI/ML models enable prediction and guide marker‐assisted selection, genomic selection, genome editing, and gene pyramiding toward improved abiotic stress tolerance, yield ...
Guangchao Sun, Jose Luis Araus, James C. Schnable, Jie Xu, Henry T. Nguyen, Yunbi Xu, Yanli Lu   +6 more
wiley   +1 more source

Embodied Architectural Geographies of Consumption and theMall Paseo ChiloéControversy in Southern Chile

Annals of the American Association of Geographers, 2019
In recent years, the geographies of architecture have expanded to include the affective and emotive dimensions of everyday life and the politics of urban space. This article explores these embodied geographies of architecture in an emerging urban landscape that has the built environment at its core: the postdictatorship retail landscape of neoliberal ...
openaire   +2 more sources

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source