Results 91 to 100 of about 2,747,378 (288)

Modern architecture in Chile. The case of Roberto Dávila Carson [PDF]

open access: yes, 2012
Modern Architecture that began in Europe at early XX Century has reached Chile through publications, but also through the travelling of Chilean architects to Europe.
Chauriye Chauriye, Rodrigo
core  

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin   +17 more
wiley   +1 more source

University of Melbourne, School of Architecture : design 2, 1964

open access: yes, 1964
Cover titleUniversity of Melbourne, School of Architecture -- coverIncomplete, contains no student work - some pages left empty [not all ...
University of Melbourne. Faculty of Architecture
core  

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Identifying competencies for emergency medicine in Chile: Modified Delphi techniqueIdentificación de competencias para la medicina de urgencia en Chile: técnica Delphi modificada

open access: yes
© 2024 The Author(s)Emergency Medicine (EM) in Latin America and other Spanish-speaking regions is in a stage of development, especially in Latin America and other Spanish speaker populations.
Brinkmann Bizama M.   +4 more
core   +1 more source

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

open access: yesAdvanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang   +14 more
wiley   +1 more source

Chile 97: análisis y opiniones

open access: yes
FLACSO, por medio de Chile 97. Análisis y opiniones, efectúa un aporte a la reflexión sobre el país en el marco latinoamericano. A través de las distintas secciones y capítulos se dan a conocer estudios, análisis y perspectivas sobre los principales ...
FLACSO Chile
core   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

open access: yesAdvanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang   +11 more
wiley   +1 more source

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