Results 41 to 50 of about 11,327,595 (293)

A Comparative Architectural Audit of Toilet Facilities in Kindergartens of Erbil, Iraqi Kurdistan

Architecture
Kindergarten toilet design influences children’s autonomy, hygiene behaviours, and psychological well-being. Yet systematic architectural evaluations in conflict-affected and developing regions remain scarce.
Nahedh Taha Al-Qemaqchi, Ashna Abdulqader Hussein   +1 more
doaj   +1 more source

5G Architectural Design Patterns [PDF]

2016 IEEE International Conference on Communications Workshops (ICC), 2016
A great part of research activities, which are related to network and system integration towards a holistic 5G system, is still ahead of us. The reason is that despite the unprecedented advancements in the wireless link capacity, the actual 5G ecosystem contains numerous diverse software and hardware technologies including a multitude of components for
Kostas Katsalis, Navid Nikaein, Eryk Schiller, Romain Favraud, Torsten Ingo Braun   +4 more
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Lexicons, Literacies and Design Futures

Temes de Disseny, 2020
As the world in which we live becomes more complex and contested, economically and politically but also in terms of rapid and long-lasting environmental change, design education faces new demands and challenges.
Andrew Morrison, Nina Bjørnstad, Einar Sneve Martinussen, Bjørn Johansen, Bastien Kerspern, Palak Dudani   +5 more
doaj   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A Process Model for the Implementation of Blockchain-Based Systems

IEEE Access
Although blockchain technology has immense potential to revolutionize various industries, its practical adoption faces significant challenges. This study tackles these hurdles by introducing a process model for the implementation of a blockchain-based ...
Muhammad Nasim Bahar, Michal Ries, Kristian Kostal   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The evolution of heritage approach in contemporary architecture and interior design from the 18th century to the 20th century

Journal of Architecture, Art & Humanistic Science
with the continuous changes in human life and the conflict between heritage and between modernity, contemporaneity and advanced technologies, we must emulate the creative thought and principles of designs used by our ancestors and mix them into what ...
Prof. Dalal Yousr-Allah Mohamed Professor of Environmental Design in Interior and Furniture Design Former Head of Decoration& Interior Architecture at The Higher Institute of Applied Arts -6th Of October, Prof. Hassan Abdo Mohamed Professor of Design at Interior Design & Furniture Department -Faculty of Applied Arts Helwan University   +1 more
doaj   +1 more source