Results 51 to 60 of about 9,847,340 (258)

Investigating the effect of architectural education on spatial cognition in primary school children

open access: yesمجله علوم روانشناختی, 2021
Background: The effectiveness of many non-architectural trainings, such as art, mathematics, and geometry, on children's spatial cognition has been demonstrated in research.
Nasim Majidizanjani   +2 more
doaj  

Application of Social Constructivism in Medical Education [PDF]

open access: yes, 2020
The purpose of this study is to discuss the main principles and concepts of social constructivism, examine the literature on the application of social constructivism in medical education, and explore the meaning and limitations of the utilization of ...
Korean Medical Education Review (의학교육논단)
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Sustainable architecture in education

open access: yes, 2021
The notion of sustainable architecture relating to human- and environment-friendly investments in view of economic and social aspects, is differently implemented in various countries. Thus, this article is focused on a five-month study on differences and
Jabłońska, Joanna, Ceylan, Salih
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Del pensamiento a la forma en Arquitectura / From thought to form in Architecture

open access: yesCuaderno de Pedagogía Universitaria, 2014
Este artículo presenta una indagación sobre los procesos de enseñanza-aprendizaje, en el tránsito del pensamiento a la forma en la asignatura ARQ-342-T Teoría de la Arquitectura I, de la Pontificia Universidad Católica Madre y Maestra. La misma parte de
Orisell Medina
doaj   +1 more source

An Education of Intuition and Process

open access: yesCubic Journal, 2020
This paper is a positioning statement and expository article describing design and fabrication projects built by students and faculty of the Hong Kong Design Institute’s (HKDI’s) Architecture programme.
Eddie Chan
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

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