Results 51 to 60 of about 1,350,073 (299)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Quels murs pour quelle école ? Architecture scolaire, normes scolaires et figures d’élèves

Éducation et Socialisation, 2017
This paper aims to contribute to knowledge on the impact of secondary schools architecture on the building of school norms and pupils profiles. It also questions the relationship between these schools and the urban architecture in which they are located.
Anne Dizerbo
doaj   +1 more source

Building a Better World with Carl Elefante [PDF]

, 2019
Carl Elefante, 2018 president of the AIA, spoke at an evening event on March 28th and provided mentorship to an architecture studio class on the 29th. Elefante believes students in the School of Architecture, Art and Historic Preservation (SAAHP) are at
Rubin, Julia
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The Rise and Fall of Visual Paradigms: An Interview with Mario Carpo

Materia Arquitectura, 2020
Interview conducted by Stephannie Fell Contreras at The Bartlett School of Architecture (March 10th, 2020) and via Zoom (April 14th, 2020) Mario Carpo is Reyner Banham Professor of Architectural History and Theory at The Bartlett School of ...
Stephannie Fell Contreras
doaj   +1 more source

Reconnecting Schools and Neighborhoods: A proposal for School Centered Community Revitalization in Baltimore Maryland [PDF]

, 2008
This project explores the concept of school-centered community as a key aspect in assisting urban renewal through architecture. It employs this concept through the architectural design of a middle school in Baltimore, Maryland that has a focus on music ...
Miller, Cody
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Organisation de l’espace scolaire et formation de l’identité chez les adolescents

Revue Internationale d’Éducation de Sèvres, 2013
This article examines the relationship between school design and adolescent identity formation. The literature and empirical studies identify three major processes involved in forming this identity: separation or individuation process; social integration
Neda Abbasi
doaj   +1 more source

The efficacy of a multi-strategy choice architecture intervention on improving the nutritional quality of high school students’ lunch purchases from online canteens (Click & Crunch High Schools): a cluster randomized controlled trial

International Journal of Behavioral Nutrition and Physical Activity, 2022
Background High school canteens are an ideal setting for public health nutrition intervention, and choice architecture strategies that facilitate the purchase of healthier foods and beverages from school canteens are recommended by the World Health ...
Tessa Delaney, Sze Lin Yoong, Hannah Lamont, Christophe Lecathelinais, Luke Wolfenden, Tara Clinton-McHarg, Rachel Sutherland, Rebecca Wyse   +7 more
doaj   +1 more source

The Educational Green: Researching Ways of Combining Professions [PDF]

, 2009
The Educational Green was an innovative 3rd year design studio held in 2007 in the faculty of Architecture, Building and Planning at the University of Melbourne. The studio both informed and was informed by the authors’ involvement in a Research Council (
Hes, Dominique, Wilks, Susan
core