Results 121 to 130 of about 130,275 (306)
Digital Preservation Services : State of the Art Analysis [PDF]
, 2012 Research report funded by the DC-NET project.An overview of the state of the art in service provision for digital preservation and curation. Its focus is on the areas where bridging the gaps is needed between e-Infrastructures and efficient and forward ...
Dobreva, Milena, Ruusalepp, Raivo
core
MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts
Advanced Science, EarlyView.We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang +5 more
wiley +1 more source
Advanced Science, EarlyView.During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen +10 more
wiley +1 more source
The Next Level of Understanding CONTENTdm [PDF]
, 2011 Hello everyone and Happy Wednesday once again! As promised from my last blog entry, I come to you with new knowledge about CONTENTdm! If you remember from my previous post, I had learned how to input the metadata in the correct fields and organize the ...
Green, Sierra R.
core +1 more source
Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response
Advanced Science, EarlyView.This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai +7 more
wiley +1 more source
Archival Collections are Important in the Study of the Biology, Diversity, and Evolution of Arboviruses. [PDF]
Evol Bioinform Online, 2016 Pyke AT, Warrilow D.
europepmc +1 more source
Technology’s Promise, the Copying of Records, and the Archivist’s Challenge: A Case Study in Documentation Rhetoric [PDF]
, 2011 Discussion of implications of electrostatic photocopying on archival appraisal, with particular attention to the macro-appraisal and collaborative models offered by Helen ...
Cox, Richard J
core +1 more source
Intelligent Stain‐Free Histology on Structural Colorimetric Nanocavities
Advanced Science, EarlyView.Chen and Gan et al. introduce a label‐free imaging platform using inexpensive Nanocavity‐on‐Silicon (NOS) slides. These slides transform subtle tissue variations into vivid structural colors, enabling high‐contrast histological imaging under a regular optical microscope. This stain‐free approach reveals morphological details comparable to traditional H&
Qizhe Chen +18 more
wiley +1 more source
From ZigZag to BigBag: Seeing the Wood and the Trees [PDF]
, 2009 This paper reports on a one year speculative research project that sought to test the technical feasibility, practical implications and usability of transforming an XML Encoded Archival Description (EAD) finding aid into an XML ZigZag™ structure and ...
Anderson, Ian G
core
Advanced Science, EarlyView.Cancer stem cells (CSCs) in non‐small cell lung cancer display pronounced plasticity and spatial heterogeneity. By integrating single‐cell and spatial transcriptomics, this study defines a DSG2‐associated CSC program and reveals a tumor‐margin niche formed with FAP+ myofibroblasts.
Guangyu Fan +8 more
wiley +1 more source