Results 141 to 150 of about 2,804,512 (374)
Entity recognition in archival descriptions
, 2022 At the moment, there is a vast amount of archival data spread across the Portuguese archives, which keeps information from our ancestors’ times to the present day. Most of this information was already transcribed to digital format, and the public can access it through archives’ online repositories.
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Advanced Science, EarlyView.Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang +12 more
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Applying Web Analytics to Online Finding Aids: Page Views, Pathways, and Learning about Users
Journal of Western Archives, 2011 Online finding aids, Internet search tools, and increased access to the World Wide Web have greatly changed how patrons find archival collections. Through analyzing eighteen months of access data collected via Web analytics tools, this article examines ...
Mark R. O'English
doaj
Advanced Science, EarlyView.This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li +15 more
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Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer
Advanced Science, EarlyView.Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen +13 more
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DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics
Advanced Science, EarlyView.This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei +12 more
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Archival description: a conceptual discussion
, 2016 Introdução: Contextualiza a atividade de descrição arquivística nos processos de organização e representação da informação. Objetivo: Apresenta como objetivo identificar o conceito de Descrição Arquivística apresentado nos artigos científicos da Ciência da Informação.
Vital, Luciane Paula, Brascher, Marisa
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