Results 201 to 210 of about 2,804,512 (374)
Multidisciplinary identification of human skeletal remains from the karst abyss in Demänovská Valley (19th-20th century calCE, Slovakia). [PDF]
Sci RepBarta P +8 more
europepmc +1 more source
Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy
Advanced Science, EarlyView.Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang +5 more
wiley +1 more source
Antonie van Leeuwenhoek and the dawn of microscopic observation: a narrative review from Delft's lens to the modern microscope. [PDF]
Appl MicroscLee H, Rhyu IJ.
europepmc +1 more source
Preliminary document analyzing and summarizing metadata standards and issues across Europe [PDF]
, 2009 Alemu, Getaneh +3 more
core
Advanced Science, EarlyView.High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao +10 more
wiley +1 more source
What does a good day look like?: An interpretable machine learning approach to the American Time Use Survey. [PDF]
PNAS NexusFolk D, Henninger M, Dunn E.
europepmc +1 more source