Results 41 to 50 of about 2,804,512 (374)
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Volatile aldehydes in libraries and archives [PDF]
Volatile aldehydes are produced during degradation of paper-based materials. This may result in their accumulation in archival and library repositories. However, no systematic study has been performed so far.
Cassar, M. +8 more
core +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Strategies for Implementing a Mass Digitization Program [PDF]
[Excerpt] In 2007, OCLC published the report Shifting Gears: Gearing Up to Get Into the Flow to bring to the forefront a much needed conversation about digitization of archival collections, and access to the rich content accessible only through paper or ...
Moore, Erik
core +1 more source
The archive of Marie-Louise Bastin: archival description
O presente artigo tem por objetivo dar a conhecer a documentação/informação do arquivo de Marie-Louise Bastin (MLB), atualmente custodiado pelo Departamento de Ciências da Vida da Faculdade de Ciências e Tecnologia da Universidade de Coimbra e pelo Museu da Ciência da mesma universidade.
Gomes, Liliana Isabel Esteves +2 more
openaire +1 more source
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
La descripción del productor y los registros de autoridades en los contextos archivísticos
La representación de la información en el ámbito de los archivos enfrenta nuevos desafíos marcados por las transiciones paradigmáticas de la Archivística.
Dunia LLanes Padrón +1 more
doaj +1 more source
Using Google Analytics Data to Expand Discovery and Use of Digital Archival Content [PDF]
This article presents opportunities for the use of Google Analytics, a popular and freely available web analytics tool, to inform decision making for digital archivists managing online digital archives content.
Szajewski, Michael
core +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source

