Results 231 to 240 of about 283,865 (345)

Suicide prevention in Latin American prisons: a multiple case study with meta-matrix of policies, programmes and protocols in 17 countries. [PDF]

BMJ Glob Health
Cifuentes-Gramajo PA, Beigel L, Bacigalupo F, Gómez-Durán G, Cortés-Jara C, Osnaya JL, Eterovich E, Cuartas-Giraldo MI, Aboaja A, Pratt D, Perry AE, Forrester A, Mundt AP.   +12 more
europepmc   +1 more source

Archival Science Commons

Archivalia, 2014
openaire   +2 more sources

Structure‐Guided Engineering of a Cas12i Nuclease Unlocks Near‐PAMless Genome Editing

Advanced Science, EarlyView.
CRISPR‐Cas nucleases are limited by PAM requirements, restricting genome accessibility. Structure‐guided engineering of the compact Cas12i nuclease SF01 produced three variants with near‐PAMless, enabling efficient editing at diverse 5'‐NNTN‐3' sites. These nucleases expand the editable portion of the human genome more than fourfold, enabling efficient
Qitong Chen, Hanlin Gou, Chao Xu, Sihan Wang, Huitao Zhang, Minglei Song, Mengge Wang, Xingkun Ji, Xiaofei Wei, Yuanyan Tan, Hehua Quan, Pengyu Luo, Hanyu Shou, Pengpeng Liu, Yafeng Liang, Jian‐Kang Zhu   +15 more
wiley   +1 more source

Narcissism and Entrepreneurial Well-Being: The Moderating Role of Equity Ranking and Industry Attention. [PDF]

Behav Sci (Basel)
Liu Y, Liang X, Zhang C, Dong W, Li X, Li H.   +5 more
europepmc   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

The permanence paradox in decentralized storage and the mutable nature of scientific knowledge. [PDF]

Sci Data
Tamang T.
europepmc   +1 more source

Historical Research and Archival Sciences in a Digital Perspective Relational Database, Data Architecture and Data Extraction in Graziani Archives Portal

Dorit Raines
openalex   +1 more source

Archives scientifiques ou archives des sciences

ArchiSHS, 2011
openaire   +2 more sources

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Consequences of Climate Change on the Emergence of Pathogenic, Environmentally Acquired Nontuberculous Mycobacteria. [PDF]

Open Forum Infect Dis
Koch TN, Banta JA, Wilsey RN, Chan ED, Crooks JL, Honda JR.   +5 more
europepmc   +1 more source