Results 31 to 40 of about 41,267 (254)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Big Data Analytics for Search Engine Optimization

Big Data and Cognitive Computing, 2020
In the Big Data era, search engine optimization deals with the encapsulation of datasets that are related to website performance in terms of architecture, content curation, and user behavior, with the purpose to convert them into actionable insights and ...
Ioannis C. Drivas, Damianos P. Sakas, Georgios A. Giannakopoulos, Daphne Kyriaki-Manessi   +3 more
doaj   +1 more source

A study of the archival system: Enhancing archive management

Journal of Commerce, Management, and Tourism Studies
This study investigates the archival management system focusing on improving its effectiveness and efficiency. The primary objectives are to evaluate the current archival practices, identify challenges and gaps, propose improvements, and enhance the overall archival management system.
Maria Bernadetha, Heni Matelda Sauw, Stela Sahetapy Engel, Maria Maria, Maria Sisilia Lou Kelen   +4 more
openaire   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Community Informatics: Library Facilitating Community Development

Tūzī yǔ dàng’àn xuékān, 2022
The new library science is moving towards the community, hoping to help its development through knowledge innovation. The relationship between the community and the library has become closer, and the librarians’ mission is to help change the community ...
Ling-Hwey Jeng, Mei-Ling Wang
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Berburu Ke Padang Datar, Berguru Kepalang Ajar: Arsip Sebagai Bahan Ajar

Sejarah dan Budaya: Jurnal Sejarah, Budaya, dan Pengajarannya, 2015
Abstrak. Keterbukaan akses atas sumber sejarah primer terutama arsip digital memudahkan para sejarawan termasuk pendidik sejarah. Hal ini akan membuat sejarah menjadi hal yang tidak monokausal, revitalisasi sumber-sumber primer, dan otonomi buku teks ...
Raistiwar Pratama Pratama
doaj   +1 more source

Kurdish Studies Archive

, 2013
Kurdish Studies Archive publishes the content of volumes 1 to 10 of Kurdish Studies. This interdisciplinary and peer-reviewed journal was dedicated to publishing high-quality research and scholarship. Since 2023 the journal has been continued as the new Kurdish Studies Journal, published by Brill, and focuses on research, scholarship, and debates in ...
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

iSchools and archival studies [PDF]

Archival Science, 2008
Whispers and rumors about the iSchool movement lead some to fear that this represents yet another shift away from the valued traditions of library schools, threatening something far different than what library science pioneers ever envisioned. Predating the iSchool movement, however, were other programmatic shifts such as those that led to the ...
Cox, RJ, Larsen, RL
openaire   +1 more source