Results 31 to 40 of about 12,829,435 (259)

Establishing the Risk Assessment Indicators of Electronic Records and Empirical Analysis of an Institution [PDF]

Journal of Library and Information Studies, 2020
The purpose of this study is to construct a risk management model of electronic records in accordance with archival appraisal elements and the theoretical framework of risk management.
Chiao-Min Lin
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Big Data Analytics for Search Engine Optimization

Big Data and Cognitive Computing, 2020
In the Big Data era, search engine optimization deals with the encapsulation of datasets that are related to website performance in terms of architecture, content curation, and user behavior, with the purpose to convert them into actionable insights and ...
Ioannis C. Drivas, Damianos P. Sakas, Georgios A. Giannakopoulos, Daphne Kyriaki-Manessi   +3 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Berburu Ke Padang Datar, Berguru Kepalang Ajar: Arsip Sebagai Bahan Ajar

Sejarah dan Budaya: Jurnal Sejarah, Budaya, dan Pengajarannya, 2015
Abstrak. Keterbukaan akses atas sumber sejarah primer terutama arsip digital memudahkan para sejarawan termasuk pendidik sejarah. Hal ini akan membuat sejarah menjadi hal yang tidak monokausal, revitalisasi sumber-sumber primer, dan otonomi buku teks ...
Raistiwar Pratama Pratama
doaj   +1 more source

Community Informatics: Library Facilitating Community Development

Tūzī yǔ dàng’àn xuékān, 2022
The new library science is moving towards the community, hoping to help its development through knowledge innovation. The relationship between the community and the library has become closer, and the librarians’ mission is to help change the community ...
Ling-Hwey Jeng, Mei-Ling Wang
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

A Digital Humanities Approach to Crime Records in Qing Dynasty Yellow Registers: Typologies, Motives, and Spatiotemporal Patterns

Tūzī yǔ dàng’àn xuékān
This study analyzes criminal case records found in Qing Dynasty Yellow Registers, employing a digital humanities approach that integrates generative artificial intelligence (GAI), Python programming, and the DocuSky platform.
Chin Shao, Chiao-Min Lin
doaj   +1 more source