Results 171 to 180 of about 41,119,821 (305)

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Cross-species conversations: the development of the AURAL-Pet coding system to capture how people talk to pets in daily life. [PDF]

Front Psychiatry
Jonkoski DS, Lorig NM, Delzio MC, Klensin A, Marsters A, Li H, Bernal AM, Mehl MR, Rodriguez KE, Bray EE.   +9 more
europepmc   +1 more source

John W. Cain Photographs

, 1982
The John W. Cain Photographs consist of late nineteenth and early twentieth century portraits, postcards, and snapshots discovered in the home of Roger M. Carroll of Akron, Ohio.
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Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Homologous recombination repair and breast cancer gene testing in prostate cancer: expert perspectives and practical guidance on best practice from sample acquisition to biomarker-informed clinical decision-making. [PDF]

Front Oncol
Compérat E, von Amsberg G, Corrigan L, Finn SP, Kristiansen G, Minucci A, Olmos D, Roubaud G.   +7 more
europepmc   +1 more source

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

Advanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang, Ke Ma, Kangqing Zuo, Pandong Lin, Tailong Zhang, Rongliang Ding, Linbo Zhang, Aonan Li, Yinchuan Wang, Yanling Huang, Jichao Feng, Guiyong Xiao, Yupeng Lu, Bing Han, Zhiqiang Wang, Ningbo Li   +15 more
wiley   +1 more source

Construction of nursing-sensitive quality indicators for hemodialysis vascular access: a Delphi study. [PDF]

Front Public Health
Zhang Y, He L, Tang S, Gao Y, Chen H, Shi M, Chen L.   +6 more
europepmc   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

Optimizing Tissue Preparation for Molecular Testing in Thyroid Tumors: A Retrospective Analysis of 177 Cases from a High-Volume Japanese Center. [PDF]

Cancers (Basel)
Hirokawa M, Higuchi M, Suzuki A, Kihara M, Akamizu T.   +4 more
europepmc   +1 more source

Alan N. Gent Files on the Panel on Technical Evaluation of NASA’s Redesign of the Space Shuttle Solid Rocket Booster, 1986-1989

Dr. Alan N. Gent was Professor of Polymer Physics in the College of Polymer Science and Polymer Engineering at The University of Akron in Akron, Ohio. He was also a member of the Panel on Technical Evaluation of NASA’s Redesign of the Space Shuttle Solid
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