Results 221 to 230 of about 41,119,821 (305)

Phenotypic Susceptibility, Resistance-Associated Genomic Determinants, and Mobile-Genetic-Element Context of Canine Otitis Externa-Associated <i>Pseudomonas aeruginosa</i> Collected in Hungary in 2010 and 2017. [PDF]

Vet Sci
Veres MA, Tóth ZA, Illés E, Mag P, Kaszab E, Fehér E, Jerzsele Á, Kerek Á.   +7 more
europepmc   +1 more source

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

Advanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang, Qixiang Zhang, Keman Liao, Xiaoyu Liu, Hongchi Zhang, Yunsheng Chen, Yuxiao Ma, Yikui Liu, Aoqian Xu, Yuhao Sun, Jiayi Chen, Liuguan Bian, Baofeng Wang   +12 more
wiley   +1 more source

Dynamic HER2 reassessment and precision sequencing after trastuzumab in HER2-positive advanced gastric cancer. [PDF]

ESMO Gastrointest Oncol
Ooki A, Shimozaki K, Yamaguchi K.
europepmc   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

Advanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang, Zhenhua Hu, Jiali Liao, Lijun Huang, Jinyu Liu, Chen Tu, Yuchen Li, Lulu Xie, Shilei Bi, Xiaobo Fang, Jingsi Chen, Lili Du, Wei Sun, Haibin Wang, Shuang Zhang, Dunjin Chen, Zhaowei Tu   +16 more
wiley   +1 more source

<i>Mycobacterium chelonae</i> as an Underrecognized Cause of Granulomatous Disease in Fish and Humans: A Molecular One Health Study. [PDF]

Pathogens
Cubeddu T, Pilloni L, Burrai GP, Sanna MA, Polinas M, Murgia C, Gerosa C, Ambu R, Fanni D, Antuofermo E.   +9 more
europepmc   +1 more source

Granzyme B PET Imaging Reveals Lgmn+ Macrophage‐Mediated Immune Evasion and Guides Immunotherapy in EGFR‐TKI‐Resistant NSCLC

Advanced Science, EarlyView.
Graphical illustration of 68Ga‐GZB PET/CT imaging reveals immune dynamics post‐EGFR‐TKI resistance in NSCLC; Lgmn+ macrophages‐derived Lgmn‐containing extracellular vesicles inhibit glycolysis, induce CD8+ T cell exhaustion, and targeting Lgmn restores immunotherapy sensitivity.
Dongliang Wang, Wenqin Luo, Qiufang Liu, Wenxuan Tang, Bin Zhu, Jiwei Chen, Qian Zhou, Shuang Tang, Xiaoping Xu, Shaoli Song   +9 more
wiley   +1 more source

Prospective cohort study identifies barriers and facilitators to point-of-care ultrasound use in an academic emergency department. [PDF]

BMJ Open Qual
Platt A, Peterson T, Peethumnongsin E, Kuchibhatla M, Theophanous RG.   +4 more
europepmc   +1 more source

A Study for Using a National Standard Meta-Data for the Local Archive

PROCEEDINGS OF THE ITE CONVENTION, 2003
Ito, Manabu, Tanno, Yoshikazu, Ishibashi, Youichi   +2 more
openaire   +1 more source

Geometry‐Encoded Soft Strain Sensing via Liquid‐Metal Transmission Lines

Advanced Science, EarlyView.
This study presents a liquid‐metal transmission‐line strain sensor that achieves intrinsic decoupling by encoding axial elongation into propagation delay. The time‐domain readout remains stable under complex off‐axis. This enables reliable, repeatable, real‐time elongation measurement in dynamic, multiaxial loading environments for wearable electronics,
Zhang Liu, Fengdeng Jin, Wenxuan Shi, Meng She, Ziqi Meng, Miao Fang, Yixin Zhang, Qianwen Dong, Wandi Yang, Lei Shi, Xujia Zhao, Feng Zhou, Bin Yao   +12 more
wiley   +1 more source

Early experiments in the making of Moravian ceramics in North Carolina c. 1770-1820. [PDF]

NPJ Herit Sci
Sarnecka Z, Bonizzoni L, Brown JM, Sarnecki J, Mazzocchi C.   +4 more
europepmc   +1 more source