Results 241 to 250 of about 25,687,323 (301)

Robust immunohistochemical detection of α-synuclein, tau and amyloid-β in human brain tissue archived for up to 78 years. [PDF]

Free Neuropathol
Just MK, Christensen KB, Wirenfeldt M, Steiniche T, Parkkinen L, Myllykangas L, Borghammer P.   +6 more
europepmc   +1 more source

Advancing Efficient Error Reduction in DNA Data Storage Systems with Deep Learning‐Based Denoising Models

Advanced Intelligent Discovery, EarlyView.
Deep learning‐based denoising models are applied to DNA data storage systems to enhance error reduction and data fidelity. By integrating DnCNN with DNA sequence encoding methods, the study demonstrates significant improvements in image quality and correction of substitution errors, revealing a promising path toward robust and efficient DNA‐based ...
Seongjun Seo, Anshula Tandon, Nguyen Kim Uyen, Quoc Nam Le, Jee‐Hyong Lee, Sung Ha Park   +5 more
wiley   +1 more source

Ensuring the future of Atlantic bluefin tuna. [PDF]

Proc Natl Acad Sci U S A
Block BA, Aalto EA, Pagniello CMLS, Whitlock RE, Stokesbury MJW, Schallert RJ, Castleton MR, Walter JF, Ferter K, Nøttestad L, Bjelland O, Maxwell HW, Drumm A, Waters C, Cermeño P.   +14 more
europepmc   +1 more source

Majority‐Voting Overlapping Method for Error Correction in DNA Data Storage

Advanced Intelligent Discovery, EarlyView.
We propose an overlapping‐based majority‐voting method for DNA data storage error correction. By aligning multiple reads and choosing the most frequent base per position, it suppresses substitution errors without prior models. Validated on synthetic and real sequencing data, it achieves high‐fidelity, scalable, and cost‐effective reconstruction ...
Thi Bich Ngoc Nguyen, Seongjun Seo, Anshula Tandon, Nguyen Kim Uyen, Thi Hong Nhung Vu, Sung Ha Park   +5 more
wiley   +1 more source

The Discovery Research Platform for Medical Humanities responds to the Wellcome Trust's report on <i>Archives, manuscripts and material culture (AMCs) in life, health, and wellbeing research</i>. [PDF]

Wellcome Open Res
Barratt H, Johnstone F, McGuire C.
europepmc   +1 more source

AI Powered Biobanks From Static Archives to Dynamic Discovery Engines

Advanced Intelligent Discovery, EarlyView.
Large language models (LLMs) provide a potential framework for transforming biobanks from static data repositories into intelligent discovery engines. By enabling unified representation and analysis of multimodal biomedical data, LLM‐based systems facilitate dynamic risk prediction, biomarker identification, and mechanistic interpretation, thereby ...
Wenzhen Yin, Yutian Feng, Wenrui Ma, Yuxin Su, Li Min, Juan Liu   +5 more
wiley   +1 more source

Detection of Adenoviral <i>E1A</i> Gene in Guthrie Cards for Insights into Pediatric Cancer Origin. [PDF]

Int J Mol Sci
Mendoza G, Guerrero R, Strunk M, Calvo C, González-Irazabal Y, Álvarez R, Gomez-Sirvent JE, López-Almaraz R, Hernández-Losa J, Ramón Y Cajal S, González-Pastor R, Martin-Duque P.   +11 more
europepmc   +1 more source

The Interoperability Challenge in DFT Workflows Across Implementations

Advanced Intelligent Discovery, EarlyView.
Interoperability and cross‐validation remain major challenges in the computational materials science. In this work, we introduce a common input/output standard that enables internal translation across multiple workflow managers—AiiDA, PerQueue, Pipeline Pilot, and SimStack—while producing results in a unified schema.
Simon K. Steensen, Tushar Singh Thakur, Manuel Dillenz, Johan M. Carlsson, Celso R. C. Rêgo, Eibar Flores, Hamidreza Hajiyani, Felix Hanke, Juan María García Lastra, Wolfgang Wenzel, Nicola Marzari, Tejs Vegge, Giovanni Pizzi, Ivano E. Castelli   +13 more
wiley   +1 more source

Variation in prehospital ACS care within a single city: a bicentric observational study (MONAH-1 subgroup analysis). [PDF]

BMC Emerg Med
Hofmann T, Baumann P, Sauer M, Schilling T, Breitling C, Schmidt C, Meyer F.   +6 more
europepmc   +1 more source

Autonomous X‐Ray Fluorescence Mapping for Nanoscale Chemical Speciation of Fine Particulate Matter

Advanced Intelligent Discovery, EarlyView.
We present X‐AutoMap, an autonomous X‐ray fluorescence mapping framework that integrates real‐time analysis with rule‐based computer vision to selectively target chemically relevant regions. By avoiding background‐dominated areas, the method reduces acquisition time by fourfold while enabling accurate particle‐level speciation.
Carlos Deleon, Dmitri Gavrilov, Peggy O’Day, Ajith Pattammattel   +3 more
wiley   +1 more source