Results 111 to 120 of about 2,442,598 (332)
Holes in the Archive - to fill or to leave, that is the question... [PDF]
, 2015 The essay features in an issue of Bright Light dedicated to the idea of the substrate, and began as a paper in one of three symposia exploring the various interpretative investigations of the substrate, and how it impacts on, and informs different ...
Melvin, Jo
core
Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS
Advanced Science, EarlyView.This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu +14 more
wiley +1 more source
“The case of detecting the proclamation, interpreting about the need to stop the war”: anti-war revolutionary activity in Omsk in 1914–1917 [PDF]
Омский научный вестник: Серия "Общество. История. Современность"This publication considers the activities of revolutionaries in Omsk in 1914–1917, which are opponents of the First World War. Despite the extensive number of works in the Soviet and post-Soviet historiography about the Siberian Bolsheviks in the pre ...
M. M. Stelmak
doaj +1 more source
Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development
Advanced Science, EarlyView.Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong +21 more
wiley +1 more source
A study of the Sunyaev-Zel'dovich increment using archival SCUBA data [PDF]
, 2007 M. Zemcov +4 more
openalex +1 more source
Workshop Review: Timescapes Secondary Analysis Workshop [PDF]
, 2011 The Timescapes Workshops were offered as three, one day events held around the UK for researchers and practitioners to learn about and interact with the Timescapes Archive. This archive forms an integral part of a five year ESRC qualitative longitudinal
Reid, K.
core +1 more source
Advanced Science, EarlyView.Triple‐negative breast cancer exhibits variable sensitivity to PRMT5 inhibition. Basal interferon signaling is identified as a key biomarker of response. PARP inhibition with olaparib induces IFN signaling, sensitizing resistant TNBC cells to PRMT5 inhibitors.
Ziwen Zhang +9 more
wiley +1 more source
Film screening and discussion: Citizen Vaclav Havel Goes on Vacation [PDF]
, 2006 This is the archive of a film screening and discussion given by Jan Novak, author and ...
Novak, Jan
core +1 more source
Advanced Science, EarlyView.This study explores how iron and manganese oxides transform sewage sludge into plant biostimulants during composting. Non‐targeted identification reveals the main species of plant biostimulants. Metagenomic analysis reveals that 2‐line ferrihydrite specifically enriches microbial genes for biosynthesis, boosting plant‐growth promoters.
Yu Zhang +7 more
wiley +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
Advanced Science, EarlyView.CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source