Results 131 to 140 of about 2,313,292 (299)
Advanced Science, EarlyView.In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin +13 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao +12 more
wiley +1 more source
Problems of Legal Regulation of Currency Circulation in Eastern Russia during the First World War
Сибирское юридическое обозрение, 2014 The survey of the overall economic and financial situation in the Eastern Russia during the First World War is presented in the article. Special attention is paid by the author to the first experience of local emissions of money surrogates.
D. I. Petin
doaj
THE MIND AND BRAIN SCHOLAR AS A HITCH-HIKER IN POST-GUTENBERG GALAXY: PUBLISHING AT 2000 AND BEYOND
, 2000 Electronic journal (e-journal) publishing has started to change the ways we think about publish-ing. However, many scholars and scientists in the mind and brain sciences are still ignorant of the new possibilities and on-going debates.
Corre, Marianne +2 more
core
Advanced Science, EarlyView.ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei +11 more
wiley +1 more source
New tricks? Old tools to solve new problems: a pilot project using UDC at the UK Data Archive [PDF]
Catalogue and Index, 2017 Suzanne Barbalet, Nathan Cunningham
doaj
Сибирское юридическое обозрение, 2014 The article deals with the analysis of the emergence of the German Chancellor’s statement at the end of the First World War in the anti-Bolshevik gazette «Sibirsky Vestnik».
M. M. Stelmak
doaj
A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity
Advanced Science, EarlyView.This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu +16 more
wiley +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
Advanced Science, EarlyView.By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Advanced Science, EarlyView.An entity‐centric foundation model, GloPath, is introduced for comprehensive glomerular lesion assessment from routine renal biopsy images. Trained on over one million glomeruli, the framework enables robust lesion recognition, grading, and cross modality diag nosis, while uncovering large‐scale clinicopathological associations.
Qiming He +28 more
wiley +1 more source