Results 151 to 160 of about 2,313,292 (299)

Multi‐Scale Mapping of Gene Expression from Whole‐slide Images for Identifying Phenotype‐Associated Subpopulations

Advanced Science, EarlyView.
BiSCALE: A pathology‐driven deep learning framework for multi‐scale gene expression prediction from whole‐slide images. It accurately infers bulk and near‐cellular spot‐level expression, links predictions to clinical phenotypes, identifies disease‐associated niches, and enables applications in risk stratification and cell‐identity annotation, providing
Hailong Zheng, Jiajing Xie, Luqi Wang, Hailong Xie, Tong Zhi, Yujia Guo, Bofeng Zhu, Dong Wang, Yu Chen   +8 more
wiley   +1 more source

FloraSyntropy-net: scalable deep learning with novel FloraSyntropy archive for large-scale plant disease diagnosis. [PDF]

Plant Methods
Khan SUR, Asim MN, Vollmer S, Dengel A.
europepmc   +1 more source

Curating Archives, Archiving Curating [PDF]

This thesis investigates the concept of archives and their role as a source for\ud curatorial work practice. It starts with an examination of Jacques Derrida's\ud concept of the archive in order to claim that every reading of the archive alters the\ud archive.
openaire  

Archives coloniales, archives colonialistes?

, 2005
Text in Portuguese from the communication to the "IV Seminário internacional de Arquivos de tradição ibérica" of the Associação latino-americana de Arquivos, at the Instituto dos Arquivos nacionais - Torre do Tombo (24-28 Oct. 2005), Reflections on the practice of the author of the police archives of the Portuguese colonisation of Mozambique from 1990 ...
openaire   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Political and intellectual legacy of Nikolai Ivanovich Astrov in Russia and in emigration. [PDF]

Front Sociol
Orchakova L, Smirnova Y, Tokareva E.
europepmc   +1 more source

Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu, Haihong Lai, Qing Yang, Chaoyue Zhang, Bin Jia, Qiyi Chen, Yuling Deng, Fen Cao, Yuyu You, Zhe Li, Dongming Kuang, Bo Li   +11 more
wiley   +1 more source

Correction: Treatment of post-vaccination optic neuritis: implications from the global SARS-CoV-2 vaccination effort. [PDF]

Graefes Arch Clin Exp Ophthalmol
Neo YN, Martinez-Alvarez L, Davagnanam I, Girafa G, Bremner F, Braithwaite T, Khaleeli Z, Nowak V, Toosy AT, Petzold A, International Consortium on Optic Neuritis (ICON).   +10 more
europepmc   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Multi-objective optimization for 3D heterogeneous WSN deployment using an enhanced Genghis Khan shark algorithm. [PDF]

Sci Rep
Houssein EH, Ibrahim IE, Wazery YM, Emam MM.   +3 more
europepmc   +1 more source