Results 21 to 30 of about 257,402 (243)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Revisiting Qualitative Data Reuse
SAGE Open, 2017 Secondary analysis of qualitative data entails reusing data created from previous research projects for new purposes. Reuse provides an opportunity to study the raw materials of past research projects to gain methodological and substantive insights.
Libby Bishop, Arja Kuula-Luumi
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Research Project for the Preservation of the Cultural and Historical Heritage
Digital Presentation and Preservation of Cultural and Scientific Heritage, 2017 The exceptional contribution of Felix Kanitz to Bulgarian scientific and cultural development is an occasion to present to Bulgarian and European public his artistic and documentary heritage, to turn again our attention to the personality and the ...
Darina Ilieva, Gabriela Vaptzarova
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Историко-географический журнал, 2022 The Upper Oka region is noted for the fact that during 16th–17th centuries it still holds the remains of the land ownership by the descendants of the princes Obolensky, Mosalsky, Vorotynsky, Volkonsky, etc., who used to own lands in the indicated region.
A. V. Deduk
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
A study on digital literacy and influencing factors among Chinese seafarers
Scientific ReportsDigital literacy and skills have become critical indicators of international competitiveness, gaining attention across all sectors. As digital transformation accelerates, the shipping industry, a pivotal center of global trade, faces new challenges.
Junhua Li +4 more
doaj +1 more source