Results 101 to 110 of about 422,561 (258)

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

open access: yesAdvanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen   +8 more
wiley   +1 more source

General cost analysis for scholarly communication in Germany : results of the "Houghton Report" for Germany [PDF]

open access: yes, 2012
Management Summary: Conducted within the project “Economic Implications of New Models for Information Supply for Science and Research in Germany”, the Houghton Report for Germany provides a general cost and benefit analysis for scientific communication ...
Bernius, Steffen   +4 more
core  

Confidentiality and Informed Consent: Issues for Consideration in the Preservation of and Provision of Access to Qualitative Data Archives

open access: yesForum: Qualitative Social Research, 2000
This paper highlights the main issues concerned with preserving fieldwork "contracts", such as informed consent agreements, as they relate to the conduct of research and the archiving of qualitative data. We pay particular attention to the techniques and
Louise Corti   +2 more
doaj  

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

open access: yesAdvanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang   +14 more
wiley   +1 more source

Predictions Regarding the Evolution Of Archiving Documents Generated by Business Entities [PDF]

open access: yes
The documents of any organization are created, modified, distributed through various routes, archived, accessed, re-delivered, re-archived. Taking into account that during the last few years the legislative framework regulating the record, inventory ...
Teodorescu, Narcisa   +1 more
core  

Qualitative and Qualitative Longitudinal Resources in Europe [PDF]

open access: yes, 2011
In April 2009 the UK Timescapes Initiative, in collaboration with the University of Bremen, organised a residential workshop to explore the nature of qualitative (Q) and qualitative longitudinal (QL) research and resources across Europe. The workshop
Bishop, Libby, Neale, Bren
core  

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang   +8 more
wiley   +1 more source

Strengthening Data Security: an Holistic Approach [PDF]

open access: yes, 2008
In the light of heightened concern around data security, this paper highlights some of the measures that can be used to develop and strengthen security in data archiving. The paper includes discussion of the different approaches that can be taken towards
Bolton, S, Woollard, M
core  

A Perspective on Interactive Theorem Provers in Physics

open access: yesAdvanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

On "Open Access" Publishers Who Oppose Open Access Self-Archiving Mandates

open access: yes, 2007
The online age has made powerful new benefits for research possible, but these benefits entail a profound conflict of interest between (1) what is best for the research journal publishing industry and (2) what is best for research, researchers ...
Harnad, Stevan
core  

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