Results 111 to 120 of about 458,612 (282)
Current Quality Assurance Practices in Web Archiving [PDF]
, 2014 This paper presents the results of a survey of quality assurance (QA) practices within the field of web archiving. To understand current QA practices, the authors surveyed 54 institutions engaged in web archiving, which included national libraries ...
Ko, Lauren +2 more
core
Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy
Advanced Science, EarlyView.A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li +11 more
wiley +1 more source
, 2016 In this paper, we propose a modified approach to realtime transactional web archiving. It leverages the web caching infrastructure that is already prevalent on web servers.
Fox, Edward A. +2 more
core
Liver Endothelia Orchestrate MASH‐Associated Macrophage Zonation Through FSTL1‐ITGA4 Axis
Advanced Science, EarlyView.Liver inflammation in MASH fundamentally hinges on the newly defined Kit/STAT2/FSTL1/ITGA4 axis. Declining endothelial Kit collapses normal hepatic zonation, driving an aberrant FSTL1 gradient that recruits pathogenic macrophages. Strikingly, targeting FSTL1‐ITGA4 with anti‐VLA4 restores spatial immune homeostasis and halts disease progression ...
Lin Sun +10 more
wiley +1 more source
Qualitative or Quantitative? Data Archiving in Documentation, Research and Teaching
Forum: Qualitative Social Research, 2005 In this article some of the conceptual and technical issues relating to data archiving in relation to documentation, research, and teaching are discussed.
Dominique Joye
doaj
Database archiving: how to keep lots of data for a very long time
, 2008 With the amount of data a business accumulates now doubling every 12 to 18 months, IT professionals need to know how to develop a system for archiving important database data, in a way that both satisfies regulatory requirements and is durable and secure.
Olson, Jack E, Olson, Jack E.
core
Advanced Science, EarlyView.A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li +13 more
wiley +1 more source
Advanced Science, EarlyView.In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin +8 more
wiley +1 more source
'Archiving should be just like an Apple', en acht andere, nuttige (?) stellingen [PDF]
, 2012 Geert-Jan van Bussel, bijzonder lector Digital Archiving & Compliance, sprak op dinsdag 16 oktober 2012 zijn lectorale rede uit in het Kohnstammzaal. Van Bussel sprak over de betrouwbaarheid van informatie en de manieren waarop ‘Digital Archiving’ en ...
Bussel, G.J. van, van Bussel, Geert-Jan
core
Advanced Science, EarlyView.A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker +11 more
wiley +1 more source