Results 31 to 40 of about 422,561 (258)

A ORIGEM DO CONCEITO DE CLASSIFICAÇÃO E SUA APLICABILIDADE NOS DOCUMENTOS DE ARQUIVO

open access: yesLexCult, 2019
The purpose of this paper is to search for the origin and development of the construction of the classification plans and how they were established in the literature and archival thinking. The focus is on identifying how,
Fernanda Maria de Andrade Ferreira
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Genealogy in the System of Modern Knowledge: Theory and Methodology of Cognitive History of O.M. Medushevskaya

open access: yesRUDN Journal of Russian History
The author analyzes the place of genealogy as a unique indicator of humanitarian culture both in historical retrospect and modern society, since the subject of its study has traditionally been universal human values - family, kinship and relationships ...
Irina V. Sabennikova
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Event Notifications and Event Logs

open access: yesInternational Journal of Digital Curation
The “Event Notifications in Value-Adding Networks” specification provides an interoperable fabric that can be used in scholarly communication to exchange messages among data nodes that make scholarly artifacts available to the network and service nodes ...
Patrick Hochstenbach   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Digital Archaeological Archiving in Baden-Württemberg, Germany: an evolving system

open access: yesInternet Archaeology, 2021
Since 2005, the Landesamt für Denkmalpflege Baden-Württemberg has been collecting semi-structured archaeological digital project data with the aim of one day turning that data into a real long-term digital archive. This process is still ongoing.
David Bibby
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Archiving of Archaeological Digital Datasets in Slovenia: historic context and current practice

open access: yesInternet Archaeology, 2021
This article presents the archiving of archaeological digital datasets in Slovenia in its historic context. The datasets discussed have been separated into three categories: non-reproducible datasets, reproducible datasets, and registries.
Benjamin Štular
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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