Results 31 to 40 of about 458,612 (282)

Rekayasa Aplikasi Pengarsipan Surat Permohonan Hak Milik Tanah Dengan menggunakan Metode Prototyping

Infotekmesin: Media Komunikasi Ilmiah Politeknik Cilacap, 2022
National Land Agency received requests for land rights every day. The letters can be submitted through two stages of acceptance and archiving. Still using conventional systems makes data retrieval requires relatively more time.
Egia Rosi Subhiyakto, Yani Parti Astuti, Danang Wahyu Utomo   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Event Notifications and Event Logs

International Journal of Digital Curation
The “Event Notifications in Value-Adding Networks” specification provides an interoperable fabric that can be used in scholarly communication to exchange messages among data nodes that make scholarly artifacts available to the network and service nodes ...
Patrick Hochstenbach, Ruben Verborgh, Herbert Van de Sompel   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Archiving Archaeological Data: Understanding current practice through case studies from established repositories

Internet Archaeology
The article describes and compares key policies and workflows from three long standing digital repositories for archaeological data: Data Archiving and Networked Services (DANS) of the Netherlands, the Swedish National Data Service (SND), and the ...
Tim Evans, Hella Hollander, Ulf Jakobsson, Valentijn Gilissen, Holly Wright   +4 more
doaj   +1 more source

A ORIGEM DO CONCEITO DE CLASSIFICAÇÃO E SUA APLICABILIDADE NOS DOCUMENTOS DE ARQUIVO

LexCult, 2019
The purpose of this paper is to search for the origin and development of the construction of the classification plans and how they were established in the literature and archival thinking. The focus is on identifying how,
Fernanda Maria de Andrade Ferreira
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Archiving New Zealand Digital Games From 80's and 90's [PDF]

, 2006
Increasingly people are moving from producing physical artifacts to digital. Digital objects are being produced and updated faster than ever before; however, every time when they are replaced, the valuable knowledge behind them is lost as well.
Yue, Cao
core   +1 more source