Results 41 to 50 of about 422,561 (258)

Design of an Archiving Information System using the Agile Scrum Method

open access: yesSistemasi: Jurnal Sistem Informasi
This study aims to design and implement a web-based archiving information system at PT Sarana Tirta Ungaran using the Agile Scrum methodology. The background of this research lies in the challenges of manual archive management, which often lead to ...
Denny Farissa Setiawan, Yani Rahardja
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Towards a national web in a federated country : a Belgian case study [PDF]

open access: yes, 2016
Although the .be domain was introduced in June 1988, the Belgian web is currently not systematically archived. As of August 2016, 1.550.147 domains are registered by DNS Belgium.
Chambers, Sally   +4 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Archiving scientific blogs with ArchivePress [PDF]

open access: yes, 2009
A poster describing the ArchivePress blog archiving approach and project, presented at the International Digital Curation Conference, London, December ...
Davis, Richard M.   +2 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Workshop Review: Timescapes Secondary Analysis Workshop [PDF]

open access: yes, 2011
The Timescapes Workshops were offered as three, one day events held around the UK for researchers and practitioners to learn about and interact with the Timescapes Archive. This archive forms an integral part of a five year ESRC qualitative longitudinal
Reid, K.
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

One Schema to Rule them All. The Inner Workings of the Digital Archive ARCHE

open access: yesMitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2018
A Resource Centre for the HumanitiEs (ARCHE) is a digital archive provided by the Austrian Centre for Digital Humanities, which is part of the Austrian Academy of Sciences.
Martina Trognitz, Matej Ďurčo
doaj   +1 more source

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