Results 101 to 110 of about 175,625,292 (210)

Scaling Web Archiving: The Challenges of Deduplication [Video]

This presentation provides insights into recent endeavors undertaken to confront challenges of duplicated content in web archiving. This recording originated from the IIPC General Assembly and Web Archiving Conference held on April 24-26, 2024 held at ...
Dempsey, Alex
core  

The Novel Viral Non‐Coding RNA LMP2A‐IT1 Promotes the Lytic Replication of EBV

Advanced Science, EarlyView.
Decades after its discovery, EBV's genome still harbours unannotated “dark matter”. LMP2A‐IT1, a novel EBV‐encoded transcript identified in this work, is strongly upregulated during lytic replication and promotes BZLF1 expression, likely through activation of inflammatory responses, thereby enhancing viral propagation in a self‐reinforcing positive ...
Zheng‐Zhou Lu, Jun‐Fei Wu, Nannan Zhu, Ming‐Hui Yang, Le‐Le Zhang, Yuan‐Tao Liu, Wei‐Jun Chen, Jin‐Kun Tang, Jia‐Wei Ge, Chao‐Bo Lei, Tao Zhang, Yu Wang, Chao‐Yun Huang, Qian Zhong, Mu‐Sheng Zeng, Yan Li   +15 more
wiley   +1 more source

Reframing bioinformatics capacity development in Africa: from training supply to research-driven demand. [PDF]

J Community Genet
Hussein J, Myovela H.
europepmc   +1 more source

Scaling Web Archiving: The Challenges of Deduplication [Presentation]

This presentation provides insights into recent endeavors undertaken to confront challenges of duplicated content in web archiving. Presentation for the IIPC General Assembly and Web Archiving Conference held on April 24-26, 2024 held at the National ...
Dempsey, Alex
core  

A Multi‐Structural Radiomic Digital Phenotyping Framework for Deciphering Preclinical Evolution of Degenerative Meniscal Tears

Advanced Science, EarlyView.
Subclinical matrix disruption precedes degenerative meniscal tears across the knee joint. A spatial compartmental radiomics model utilizing 3D‐DESS MRI captures early osteochondral destabilization, accurately predicting incident tears up to four years pre‐collapse. Feature attributions uncover coordinated chondral and osseous alterations, advancing non‐
Shengfa Li, Hao Liu, Yanbin Zhu, Hang Zhang, Qifeng Tao, Wenbo Zhao, Xin Miao, Shanshan Yang, Tianyu Chen, David Hunter, Changhai Ding, Ting Wang, Juan Wang, Wei Chen   +13 more
wiley   +1 more source

CODE beyond FAIR: a roadmap for reusable research software. [PDF]

Sci Data
Di Cosmo R, Granger S, Hinsen K, Jullien N, Le Berre D, Louvet V, Maumet C, Maurice C, Monat R, Rougier NP.   +9 more
europepmc   +1 more source

Reln mRNA Delivery Drives Neurogenic Bone Regeneration by Orchestrating Schwann Cell‐Mediated Exosomal Trafficking

Advanced Science, EarlyView.
MSNs serve as a robust vehicle for CRISPRa‐mediated Reln induction, driving bone repair through the establishment of a neurogenic‐supportive microenvironment. ABSTRACT Neurogenic bone regeneration is essential for the effective restoration of bone tissue functionality, while the mechanisms and new strategies underlying neurogenic bone regeneration ...
Shuai Lin, Qianwen Li, Duo Liu, Mingzhao Li, Han Zhang, Liujing Chen, Yan Yu, Jiuhui Jiang, Chun Xu, Ruili Yang   +9 more
wiley   +1 more source

Single‐Cell Insights Into Pathogenic Profile of Orchitis and SREBP2‐Associated Cholesterol Dysregulation in Spermatogenic Failure

Advanced Science, EarlyView.
A first single‐cell atlas of human orchitis reveals coordinated germ‐cell loss, somatic niche dysfunction, and immune‐metabolic remodeling. Aberrant SREBP2 activation in testicular somatic cells emerges as a central pathogenic node, while Fatostatin‐mediated inhibition of the SREBP pathway improves spermatogenesis, fibrosis, and lipid accumulation in a
Yanlin Tang, Qiaoling Jiang, Yuwen Liu, Wenxiu Zhang, Lina Cui, Xiaojian Lu, Ziyan Zhuang, Jianxing Cheng, Songzhan Gao, Yangyi Fang, Kai Hong, Jie Qiao, Xiaoyan Wang, Hui Jiang, Zhe Zhang, Jingtao Guo, Qiang Liu   +16 more
wiley   +1 more source

Exploring the Value Realization and Management of Healthcare Data Elements in the Context of New Quality Productive Forces. [PDF]

Health Care Sci
Yu Z, Wei J, Wang J, Lu J, Cao P.
europepmc   +1 more source

Web Archiving for Preserving the Digital Memory of Brazil [Video]

Recording of a presentation that explores the importance of web archiving for preserving this history, enabling access to historical information, and preventing data loss of Brazil's internet history and digital content.
Rockembach, Moises, Ferrigolo, Jonas
core