Results 161 to 170 of about 680,036 (364)

Sedimentary DNA from lake depocenters maximizes detection of catchment vegetation

Communications Earth & Environment
Sedimentary DNA is becoming an invaluable tool for biodiversity assessments across spatial and temporal scales. Accurate interpretation, however, requires a clear understanding of its origin and taphonomy, from transport to preservation processes within ...
Tulug Gulce Ataman, Youri Lammers, Inger Greve Alsos, Dilli Prasad Rijal, Antony G. Brown   +4 more
doaj   +1 more source

Arctic Sea Ice Volume Export Through Fram Strait From 1992 to 2014 [PDF]

, 2020
Gunnar Spreen, Laura de Steur, Dmitry Divine, Sebastian Gerland, Edmond Hansen, R. Kwok   +5 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Additional file 6 of Metagenome-assembled genomes of phytoplankton microbiomes from the Arctic and Atlantic Oceans

, 2022
Anthony Duncan, Kerrie Barry, Chris Daum, Emiley A. Eloe‐Fadrosh, Simon Roux, Katrin Schmidt, Susannah G. Tringe, Klaus-Ulrich Valentin, Neha Varghese, Asaf Salamov, Igor V. Grigoriev, Richard M. Leggett, Vincent Moulton, Thomas Möck   +13 more
openalex   +1 more source

Focus on Arctic change: transdisciplinary research and communication [PDF]

, 2023
Ylva Sjöberg, Frédéric Bouchard, Susanna Gartler, Annett Bartsch, Donatella Zona   +4 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Are Large‐Scale Differences in Temperature and Reindeer Management Regime Affecting the Quality of Reindeer's Summer Forage?

Ecology and Evolution
The chemical balance between essential nutrients and defense compounds in plants determines the quality of the forage available to herbivores and can be modified by both environmental conditions and herbivores themselves.
Fanny Berthelot, Audun Stien, Eeva M. Soininen, Torkild Tveraa, Hanna Böhner, Kari Anne Bråthen   +5 more
doaj   +1 more source

Estimating Spatial Changes Over Time of Arctic Sea Ice using Hidden 2×2 Tables

, 2018
Bohai Zhang, Noel Cressie
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source