Results 161 to 170 of about 336,642 (296)

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Arctic Ocean Acidification 2013: An Overview

, 2014
Report presenting a summary of the first comprehensive assessment of Arctic Ocean acidification (AOA) conducted by the Arctic Monitoring and Assessment Programme (AMAP).
Arctic Monitoring and Assessment Programme
core  

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Back to the roots: Fine-scale insights into adaptive foraging by a high-Arctic large herbivore. [PDF]

Ecology
Dwinnell SPH, Djurberg E, Eikeland O, Loe LE, Albon SD, Beumer LT, Pedersen ÅØ, Kamenova S, van der Wal R.   +8 more
europepmc   +1 more source

Genetically Programmed Shape‐Morphing of Engineered Living Materials

Advanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker, Yuchen Liu, Miguel Baños, Rosanne Schmachtenberg, Mahmudul Hasan, Claudia Fink‐Straube, Luai R. Khoury, Wilfried Weber   +7 more
wiley   +1 more source

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

Advanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng, TzuChun Chung, Katpady Akhil Tantry, Siyu Wu, Jing Tian, Yunqi Cui, Lanyu Li, Yongzan Zhou, Zhilei Zhang, Zhe Su, Gaili Cao, Kun‐Wei Yeh, Ruipeng Li, Xianghui Xiao, Adam F. G. Leontowich, Yuan‐Yu Hsueh, Zhao Pan, Kam C. Tam, Badri Narayanan, Song Li, Yimin. A. Wu   +20 more
wiley   +1 more source

Resident and Migratory Falcons' Breeding Phenology and Productivity Respond Differently to Weather and Climate Change Across the Arctic. [PDF]

Glob Chang Biol
Gulotta NA, Falk K, Ambrose S, Bakner NW, Bente PJ, Booms TL, Burnham KK, Carrière S, Henderson MT, Kharitonov S, Kondratyev AV, Kulikova O, Lindberg P, Lindström BO, Mechnikova S, Mossop D, Møller S, Nielsen ÓK, Nilsson K, Ollila T, Orrhult S, Pokrovsky I, Restani M, Robinson BW, Rosenfield RN, Swem T, Wightman PH, Huffeldt NP.   +27 more
europepmc   +1 more source

Unique Role of Microstructure of a Bioimplant Zinc Alloy and Protein Content of Simulated Body Fluid in Corrosion and Fracture

Advanced Functional Materials, EarlyView.
BSA addition to physiological solutions enhances resistance of a Zn alloy to stress corrosion cracking (SCC) but reduces its corrosion resistance. Extended surface characterization explains the contrasting influences on corrosion and SCC. Unexpectedly, the alloy suffers transgranular SCC (TGSCC), despite extensive grain boundary precipitation. Thorough
RK Singh Raman, Syed Hussain Wajahat, Saad Al‐Saadi, Robin E. Schäublin, Peng Zeng, Solomon Ansah, Jixing Lin, Xian Tong, Cuie Wen, Jörg F. Löffler   +9 more
wiley   +1 more source

On the relevance of serial cyclone clustering for Arctic sea ice. [PDF]

Nat Commun
Aue L, Tiedeck S, Finocchio P, Vihma T, Uotila P, Spreen G, Rinke A.   +6 more
europepmc   +1 more source

High‐Efficiency Quantum Defect Generation in Carbon Nanotubes via Oxygen‐Free Photochemistry

Advanced Functional Materials, EarlyView.
We show that oxygen plays an important role in quantum defect formation in carbon nanotubes and identify reaction conditions to create a range of different quantum defects for photonics and biosensing. ABSTRACT Single‐walled carbon nanotubes (SWCNTs) offer potential for a wide range of applications from optoelectronic devices to biomedical diagnostics.
Christina Derichsweiler, Valeriia D. Andreeva, Jan Stegemann, Julia Ackermann, Janus A. C. Wartmann, Svenja Herbertz, Sebastian Kruss   +6 more
wiley   +1 more source