Results 161 to 170 of about 577,992 (312)

Role of Atlantic multidecadal variability in modulating Arctic sea ice loss and wetting. [PDF]

Sci Adv
Cai Z, You Q, Screen JA, Chen HW, Zhang R, Zuo Z, Chen D, Cohen J, Kang S, Ma W, Gulev SK, Moore GWK, Zhang R.   +12 more
europepmc   +1 more source

Current Events [PDF]

This lesson on the cause of currents and water circulation in the Arctic Ocean will require students to investigate the influence of salinity and temperature on the density of seawater to determine what factors drive water circulation in the Arctic Ocean.

core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Arctic and Boreal Wildfires Impact Climate by Releasing Ancient Carbon and Light-Absorbing Particles. [PDF]

Environ Sci Technol
Ruppel MM, Somero M, Sippula O, Ihalainen M, Louhisalmi J, Tissari J, Haghipour N, Ström J, Väliranta M, Köster K, Vakkari V, Jaars K, Huang L, Smittenberg RH.   +13 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Seasonal bromate formation in the Arctic snowpack: Implications for the bromine biogeochemical cycle. [PDF]

Sci Adv
Frassati S, Barbaro E, Cozzi G, Turetta C, Scoto F, Rossetti C, Roman M, Feltracco M, Kim K, Burgay F, Saiz-Lopez A, Francisco JS, Van Pelt W, Wang F, Cappelletti D, Lerda S, Bistoni G, De Angelis F, Barbante C, Gambaro A, Spolaor A.   +20 more
europepmc   +1 more source

Arctic Sanitation

American Journal of Public Health and the Nations Health, 1949
openaire   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Development and Laboratory Validation of a Field-Deployable CRISPR-Cas12a eDNA Assay for Phylogeographic Lineage Detection in Arctic Char (Salvelinus alpinus). [PDF]

Mol Ecol Resour
Walsh DJ, Hynes R, Guo W, Surgenor C, Prodöhl PA, Parle-McDermott A.   +5 more
europepmc   +1 more source