Results 191 to 200 of about 577,992 (312)

Quantifying Arctic-boreal methane emissions using atmospheric observations and a global inverse model. [PDF]

NPJ Clim Atmos Sci
Basso LS, Rödenbeck C, Brovkin V, Georgievski G, Heimann M, Göckede M.   +5 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Recent postglacial population expansions may explain a surprising lack of lineage splitting in Arctic meiobenthic flatworms. [PDF]

BMC Ecol Evol
Wernström JV, Kwan YH, Vonnahme TR, Glud RN, Altenburger A.   +4 more
europepmc   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Pan-Arctic Peatlands Have Expanded During Recent Warming. [PDF]

Glob Chang Biol
Handley J, Fewster RE, Sim TG, Hodson S, Parker B, Crichton K, Charman D, Anderson K, Garneau M, Väliranta M, Beilman DW, Swindles GT, Aquino-López M, Blaauw M, Comas X, Levesque E, Maire V, Addis H, Amesbury M, Fortier D, Mleczko M, Gallego-Sala A.   +21 more
europepmc   +1 more source

Arctic paws [PDF]

Medical Humanities, 2017
openaire   +2 more sources

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Stratospheric precursor induces wintertime phase reversal of the "warm Arctic-cold Eurasia" pattern. [PDF]

Nat Commun
Zhang Y, Yin Z, Tian W, He S, Hsu P.
europepmc   +1 more source

Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke, Petra Steinacker, Steffen Halbgebauer, Patrick Oeckl, Geert Mayer, Markus Otto   +5 more
wiley   +1 more source

Differences in Prokaryotic Community Composition Between Two Climatically Contrasting Years in an Arctic Fjord Ecosystem. [PDF]

Environ Microbiol Rep
Lopes E, Semedo M, Bailey A, Assmy P, Magalhães C.   +4 more
europepmc   +1 more source