Results 131 to 140 of about 37,275 (284)
Canada in a Climate Disrupted World [PDF]
, 2017 Climate change has already begun impacting economies and societies across the globe, and its impacts are expected to increase into the future. Adaptation to climate change is and will continue to be one of the greatest policy challenges facing the ...
Dalby, Simon +3 more
core +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Temperature selectivity in Icelandic and Northeast-Arctic cod
, 2021 Increasing water temperatures are predicted worldwide, with high amplitudes in the Arctic and sub-Arctic regions exceeding predictions for other regions. An understanding how Atlantic cod (Gadus morhua) reacted to changing environmental conditions in the past is essential for predicting re-distribution under climate change.
openaire +1 more source
A Look at Important Marine Areas in the U.S. Beaufort and Chukchi Seas: Ecologically rich places to protect in the Arctic Ocean [PDF]
, 2016 Sound decision-making about the future of the U.S. Arctic Ocean must include an understanding of how its marine ecosystems function. Although all areas of the U.S. Chukchi and Beaufort seas contribute to ecological integrity, some are especially vital to
core
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Arctic ScienceEastern Beaufort Sea belugas face threats from increasing vessel traffic and decreasing availability of Arctic cod driven by climate change. This necessitates an improved understanding of the environmental drivers of their foraging habitat suitability to
Luke Storrie +4 more
doaj +1 more source
PICES Press, Vol. 20, No. 1, Winter 2012 [PDF]
, 2012 •2011 PICES Science: A Note from the Science Board Chairman (pp. 1-6) •2011 PICES Awards (pp. 7-9) •Beyond the Terrible Disaster of the Great East Japan Earthquake (pp. 10-12) •A New Era of PICES-ICES Scientific Cooperation (p.
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FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
, 1957 The shoals of skrei ( i.. e. large mature cod) which each winter migrate from the Barents Sea to the spawning grounds on the Norwegian coast have always been the most important resources fitr the cod fisheries of North Norway. It is therefore with great concern that the Norwegian authorities have noted the marked decline which has taken place in the ...
openaire +1 more source