Results 121 to 130 of about 37,275 (284)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Ecological adaption of reproduction in Arctic cod
, 1984 A recent period (1977-1982) of cold climate in the Barents Sea resulted in a greatly reduced feeding area available for the Arctic cod and in consistent low recruitment. With the start of a warmer period in 1982/83 the area and potential for production of cod biomass expands and recruitment has increased.
Sætersdal, Gunnar, Loeng, Harald
openaire +1 more source
Sludge Production and Disposal for Small Cold Climate Bio-Treatment Plants [PDF]
, 1972 Ultimate disposal of wastewater sludge has long been a problem which to a large degree has been ignored. Haney (1971) stated that: "Until process sludge can be handled with minimum environmental impact, we cannot claim to have a viable wastewater ...
Tilsworth, Timothy
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Ocean warming and acidification may drag down the commercial Arctic cod fishery by 2100. [PDF]
PLoS One, 2020 Hänsel MC +5 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Migratory behaviour of reared Norwegian coastal cod and north east Arctic cod
, 1995 This paper is based on experiments to test if differences in migratory behaviour of Norwegian coastal cod and north east Arctic cod is related to parental origin or, alternatively, is related to the environmental experienced during the premature stages. Earlier experiments have shown that when wild fish from the two groups are transplanted and released
Godø, Olav Rune, Totland, Atle
openaire +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Shipping alters the movement and behavior of Arctic cod (Boreogadus saida), a keystone fish in Arctic marine ecosystems. [PDF]
Ecol Appl, 2020 Ivanova SV +9 more
europepmc +1 more source
Seabird predation on Arctic cod during summer in the Canadian Arctic [PDF]
Marine Ecology Progress Series, 2012 JK Matley, AT Fisk, TA Dick
openaire +1 more source