Results 101 to 110 of about 37,275 (284)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A review of chlorinated paraffin contamination in Arctic ecosystems

open access: yesEmerging Contaminants, 2019
Chlorinated paraffins (CPs) present a complex mixture of congeners which are often analysed and assessed as short-, medium- and long-chain CPs, i.e. ΣSCCP (C10–C13), ΣMCCP (C14–C17) and ΣLCCP (≥C18).
Katrin Vorkamp   +4 more
doaj   +1 more source

Advances in methods for determining fecundity: application of the new methods to some marine fishes [PDF]

open access: yes, 2009
Estimation of individual egg production (realized fecundity) is a key step either to understand the stock and recruit relationship or to carry out fisheries-independent assessment of spawning stock biomass using egg production methods.
Dominguez, Rosario   +7 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Genomic architecture and population structure of Boreogadus saida from Canadian waters

open access: yesScientific Reports
The polar cod, Boreogadus saida, is an abundant and ubiquitous forage fish and a crucial link in Arctic marine trophic dynamics. Our objective was to unravel layers of genomic structure in B.
Trevor T. Bringloe   +7 more
doaj   +1 more source

Ecosystem structure and function of the North Water Polynya

open access: yesArctic Science
The North Water Polynya is one of the most productive Arctic regions on Earth, sustaining the world's northernmost Inuit communities for millennia. The polynya is a large and persistent region of open water surrounded by sea ice and exhibits high primary
Andrea Bryndum-Buchholz   +4 more
doaj   +1 more source

Biological reference points for North-East Arctic cod and haddock [PDF]

open access: yesICES Journal of Marine Science, 1992
It has been suggested by ACFM that Fmed might be preferable to Fmax as a biological reference point for the North-East Arctic cod. However, the Fmed level of more than twice Fmax appeared high, and it was known to have been based on biased historie SSB estimates.
openaire   +2 more sources

HARVEST FUNCTIONS: THE NORWEGIAN BOTTOM TRAWL COD FISHERIES [PDF]

open access: yes
A detailed and comprehensive set of catch and effort data for the cod fisheries of 18 Norwegian bottom trawlers have been obtained for the period 1971–85, a period with few binding quota restrictions on vessel operations.
Eide, Arne   +3 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

SHARING THE NORTHEAST ARCTIC COD: POSSIBLE EFFECTS OF CLIMATE CHANGE [PDF]

open access: yesNatural Resource Modeling, 2008
. The Northeast Arctic cod inhabits the exclusive economic zones of Norway and Russia and migrates extensively between these zones. The stock is shared evenly between the two countries, with a small allocation to third countries. Higher temperatures in the Barents Sea and the Norwegian Sea are expected to affect the stock, probably increasing its size ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy