Results 81 to 90 of about 37,275 (284)
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Results of complex surveys in the East Siberian Sea in August 2015
Data on oceanographic conditions, composition of plankton communities, benthic and demersal fish and invertebrates in the southern East Siberian Sea are presented by results of the complex survey conducted in August 2015, The bottom trawl survey assessed
Igor I. Glebov +6 more
doaj +1 more source
Bio-Processes of the Oxidation Ditch When Subjected to a Sub-Arctic Climate [PDF]
Alaska's far northern area is sparsely populated primarily because of a severe climate which varies from northern temperate to Arctic. Construction and power costs are high. Skilled operating personnel are scarce and expensive, if available. Receiving
Murphy, R. Sage, Ranganathan, K. R.
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Adapting to Environmental and Social Change: Subsistence in Three Aleutian Communities [PDF]
Our surroundings and society are both constantly evolving. Some changes are due to natural processes. People are responsible for other changes, because of what we do—for example, increasing the size of the population, expanding technology, and ...
Berman, Matthew, Schmidt, Jennifer
core
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Cumberland Sound, an inlet on Baffin Island, Nunavut, Canada, is undergoing changes in sea ice cover, which is affecting the marine food web. A small population of beluga whales Delphinapterus leucas inhabits Cumberland Sound year round and this ...
Watt, CA, Orr, J, Ferguson, SH
doaj +1 more source
Nordostarktische Fischbestände - Fangempfehlungen für 1998 [PDF]
The results of the assessments on North-east fish stocks of cod, haddock, saithe, redfish and Greenland halibut by the ICES ”Arctic Fisheries Working Group” in 1997 are presented.
Schöne, Rüdiger
core
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Results of multidisciplinary survey in the Laptev Sea in August-September, 2015
Data on oceanographic conditions and species composition of plankton, benthic and demersal fish and invertebrates are presented, obtained in the complex survey over the external shelf of the Laptev Sea in August-September 2015.
Igor I. Glebov +6 more
doaj +1 more source

