Results 31 to 40 of about 2,416 (260)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Fisheries-induced evolution in Northeast Arctic cod
, 2005 We explore the evolutionary effects of fisheries on North-East Arctic (NEA) cod. It has earlier been shown that fisheries can change the cod’s age and size at maturation in two ways: first, by reducing the biomass, which may lead to faster individual growth and thereby earlier maturation (through phenotypic plasticity), and secondly, by altering the ...
Eikeset, Anne Maria +2 more
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Arctic ScienceThe Arctic is undergoing rapid declines in sea ice and changes in Arctic ecosystems. The diet of one of the Arctic’s most abundant seabirds, the black-legged kittiwake (Rissa tridactyla), has been used as an indicator of ecosystem changes in the European
Julia E. Baak +6 more
doaj +1 more source
Barents Sea Fisheries – the IUU Struggle
Arctic Review on Law and Politics, 2010 Considerable fishing operations occur in the European part of the Arctic Ocean, especially in waters under Norwegian and Russian jurisdiction, and regional states have recently made important advances in combating illegal, unreported, and unregulated ...
Olav Schram Stokke
doaj +1 more source
A Multi-Region and Multi-Period Harvest Schedule of the Trawl Fleet
Frontiers in Marine Science, 2022 Under the individual vessel quota regulations, the expected economic return of a multi species fishery is influenced by an array of a multi-component choice such as targeted species, landings per haul, harvesting time and its location.
Tannaz Alizadeh Ashrafi +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source