Results 51 to 60 of about 4,907 (289)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Arctic and red fox population responses to climate and cryosphere changes at the Arctic’s edge

Oecologia, 2023
Abstract Responses of one species to climate change may influence population dynamics of others, particularly in the Arctic where food webs are strongly linked. Specifically, changes to the cryosphere may limit prey availability for predators.
Jacqueline S. Verstege, Sean M. Johnson-Bice, James D. Roth   +2 more
openaire   +2 more sources

Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke, Petra Steinacker, Steffen Halbgebauer, Patrick Oeckl, Geert Mayer, Markus Otto   +5 more
wiley   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Impact of spatial and temporal resource distribution on rabies dynamics in the Arctic

Arctic Science
In the Arctic, rabies is endemic in the Arctic fox (Vulpes lagopus), posing a significant and ongoing health risk for people and domestic animals. The mechanisms by which rabies is maintained within the low-density fox populations in the Arctic remain ...
Agathe Allibert, Francois Viard, Caroline C. Sauvé, Audrey Simon, Erin E. Rees, Patrick A. Leighton   +5 more
doaj   +3 more sources

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Extreme events, trophic chain reactions, and shifts in phenotypic selection

Scientific Reports, 2023
Demographic consequences of rapid environmental change and extreme climatic events (ECEs) can cascade across trophic levels with evolutionary implications that have rarely been explored.
Kate Layton-Matthews, Stefan J. G. Vriend, Vidar Grøtan, Maarten J. J. E. Loonen, Bernt-Erik Sæther, Eva Fuglei, Brage Bremset Hansen   +6 more
doaj   +1 more source

What Do Large Language Models Know About Materials?

Advanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer, Thomas Wallmersperger, Gianaurelio Cuniberti   +2 more
wiley   +1 more source

Note on the Arctic Fox (Canis lagopus) [PDF]

Nature, 1903
A RATHER peculiar error in regard to this animal seems in danger of being perpetuated in certain contemporary literature, in which it is stated that, while in the other regions of its distribution the Arctic fox generally acquires a white winter coat, in Iceland this change never takes place, but that all the foxes there are blue.
openaire   +2 more sources

Cryosphere changes drive an Arctic fox decline at the Arctic’s edge

, 2022
Abstract Responses of one species to changing climate may influence population dynamics of others, particularly in the Arctic where food webs are strongly linked. Specifically, changes to the cryosphere can limit prey availability for predators. We examined Arctic fox ( Vulpes lagopus
Jacqueline S Verstege, James Roth
openaire   +1 more source