Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Late-Pleistocene Syngenetic Permafrost in the CRREL Permafrost Tunnel, Fox, Alaska [PDF]
, 2008 contributing authors: Bjella, K.L., Bray, M.T., Collins, C.M., Douglas, T.A., Fortier, D., French, H.M., Kanevskiy, M.Z., Shur, Y.L.Late-Pleistocene syngenetic permafrost exposed in the walls and ceiling of the CRREL permafrost tunnel consists of ice-and
French, H.M. +2 more
core
Preferences, Perceptions, and Veto Players: Explaining Devolution Negotiation Outcomes in the Canadian Territorial North [PDF]
, 2012 Since the early part of the 20th century, the federal government has engaged in a long and slow process of devolution in the Canadian Arctic. Although the range of powers devolved to the territorial governments has been substantial over the years, the ...
Abele +22 more
core +2 more sources
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Impact of spatial and temporal resource distribution on rabies dynamics in the Arctic
Arctic ScienceIn the Arctic, rabies is endemic in the Arctic fox (Vulpes lagopus), posing a significant and ongoing health risk for people and domestic animals. The mechanisms by which rabies is maintained within the low-density fox populations in the Arctic remain ...
Agathe Allibert +5 more
doaj +3 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Arctic fox (Alopex lagopus) from the North Sea [PDF]
, 2018 The first record of arctic fox Alopex lagopus (Linnaeus, 1758) from the Eurogeul area (North Sea) is reported based on a distal humerus fragment collected by private collectors from dredged sediments on ‘De Zandmotor’. It was radiocarbon dated to 29,900 +
Langeveld, Bram W. +2 more
core +7 more sources
Permafrost hydrology in changing climatic conditions: seasonal variability of stable isotope composition in rivers in discontinuous permafrost [PDF]
, 2015 Role of changing climatic conditions on permafrost degradation and hydrology was investigated in the transition zone between the tundra and forest ecotones at the boundary of continuous and discontinuous permafrost of the lower Yenisei River.
Nyland, Kelsey E. +7 more
core +1 more source
Influence of cold on host-parasite interactions. [PDF]
, 1963 pt.
Arctic Aeromedical Laboratory (U.S.) +2 more
core +2 more sources
Cryosphere changes drive an Arctic fox decline at the Arctic’s edge
, 2022 Abstract Responses of one species to changing climate may influence population dynamics of others, particularly in the Arctic where food webs are strongly linked. Specifically, changes to the cryosphere can limit prey availability for predators. We examined Arctic fox ( Vulpes lagopus
Jacqueline S Verstege, James Roth
openaire +1 more source