Results 51 to 60 of about 92,465 (281)

Pyroptosis‐Inducing Engineered Microparticles for Cancer Immunotherapy

Advanced Science, EarlyView.
Engineered microparticles co‐delivering geldanamycin and dual nanobodies induce targeted pyroptosis and block PD‐L1 and CD47 pathways, reprogramming the tumor microenvironment and achieving potent antitumor immunity in lung cancer models with minimal toxicity.
Tianli Hao, Zihan Deng, Yufei Liu, Li Liu, Deqiang Deng, Muyang Yang, Yuanyuan Geng, Yao Sun, Beilei Yue, Jonathan F. Lovell, Yushuai Liu, Lisen Lu, Honglin Jin   +12 more
wiley   +1 more source

Vitamin D status of northern indigenous people of Russia leading traditional and “modernized” way of life [PDF]

International Journal of Circumpolar Health, 2014
Background: Vitamin D status in groups of northern indigenous people of Russia leading close to traditional (seminomadic reindeer herding), post-traditional (in settlements) or “modernized” (in towns) way of life was analysed.
Andrew Kozlov, Yulia Khabarova, Galina Vershubsky, Yulia Ateeva, Vadim Ryzhaenkov   +4 more
doaj   +1 more source

Improving access to lymphatic filariasis MMDP services through an enhanced evidence-based, cascaded training model for health worker capacity strengthening in Ghana: an evaluation study

Frontiers in Tropical Diseases, 2023
IntroductionGhana has made significant progress in reducing the transmission rate of lymphatic filariasis. However, very little progress has been made in the provision of morbidity management and disability prevention (MMDP) services, which is one of the
Collins Stephen Ahorlu, Solomon Abotiba Atinbire, Kojo Mensah Sedzro, Bright Alomatu, Dziedzom K. de Souza, Kofi Asamenyi-Mensah, Joseph Opare, Paul Saunderson, Stefanie Weiland   +8 more
doaj   +1 more source

Modeling raccoon (Procyon lotor) habitat connectivity to identify potential corridors for rabies spread [PDF]

, 2017
The United States Department of Agriculture (USDA), Animal and Plant Health Inspection Service (APHIS), Wildlife Services National Rabies Management Program has conducted cooperative oral rabies vaccination (ORV) programs since 1997.
Algeo, Timothy P., Atwood, Todd, Caron, Rosemary M., Chipman, Richard B., Ducey, Mark J., Palace, Michael, Recuenco, Sergio, Slate, Dennis   +7 more
core   +1 more source

The Analysis of Existing Experience for the Ethnobotanical Information System [PDF]

, 2019
Ethnobotanical researches reflect the conventional learning of a region. Over the previous decade, medical plants which used for healing indigenous people has become a significant notion among the people and impacted improvement of scientific and ...
Hamidova, L. F. (Laman)
core   +3 more sources

Tropical Medicine in China: Bibliometric Analysis Based on Web of Science (2010–2019)

Journal of Tropical Medicine, 2021
Purpose The current study quantitatively assessed research trends in tropical medicine in China via a bibliometric method, which used the Web of Science database to analyse the research-based literature related to tropical medicine published from 2010 to
Zhen Li, J. Xue, B. Zheng
semanticscholar   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Trends in life expectancy and age-specific mortality in England and Wales, 1970–2016, in comparison with a set of 22 high-income countries: an analysis of vital statistics data

The Lancet Public Health, 2019
Summary: Background: Since 2010, the rate of improvement in life expectancy in the UK has slowed. We aimed to put this trend in the context of changes over the long term and in relation to a group of other high-income countries. Methods: We compared sex-
David A Leon, ProfPhD, Dmitry A Jdanov, PhD, Vladimir M Shkolnikov, PhD   +2 more
doaj   +1 more source

Not all surveillance data are created equal—A multi‐method dynamic occupancy approach to determine rabies elimination from wildlife [PDF]

, 2019
1. A necessary component of elimination programmes for wildlife disease is effective surveillance. The ability to distinguish between disease freedom and non‐detection can mean the difference between a successful elimination campaign and new epizootics ...
Cliquet F., Gelman A., Glueck T. F., Gruen B., Homer C., MacKenzie D. I., Manning S. E., Mörner T., R Core Team, Ronald G., Rupprecht C.   +10 more
core   +2 more sources

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

Advanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang, Kun Li, Lihong Liu, Linsen Zeng, Qifeng Deng, Jiacheng Huang, Xiaoran Dong, Xin Wang, Jianwei Liang, Hongchao Liu, Hong Peng, Yuxin Lin, Xiaolu Xie, Yuzhen Ye, Tiefeng Xu, Zhaohuan Wang, Chun‐Mei Li, Deyin Guo   +17 more
wiley   +1 more source