Results 91 to 100 of about 2,958,713 (246)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
NUUK DECLARATION On the occasion of the 7th Ministerial Meeting of The Arctic Council, May 2011 [PDF]
, 2011 NUUK DECLARATION On the occasion of the Seventh Ministerial Meeting of The Arctic Council 12 May 2011, Nuuk ...
Arctic Council, -
core +1 more source
BMC Cardiovascular DisordersBackground Psychosocial stress is increasingly recognized as an independent risk factor for cardiovascular disease. However, the long-term impact of cumulative stressful life events on the risk of myocardial infarction (MI) and mortality in the general ...
Geir Fagerjord Lorem +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
TROMSØ DECLARATION On the occasion of the Sixth Ministerial Meeting of The Arctic Council April, 2009 [PDF]
, 2009 TROMSØ DECLARATION On the occasion of the Sixth Ministerial Meeting of The Arctic Council.
Arctic Council, -
core +1 more source
BMC PsychiatryBackground Mental health problems are highly prevalent in prison populations. Incarcerated persons generally come from disadvantaged backgrounds and are living under extraordinary conditions while in prison. Their healthcare needs are complex compared to
Line Elisabeth Solbakken +2 more
doaj +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
The multifaceted role of autophagy and mitophagy in cardiovascular health and disease
Autophagy ReportsThe cardiovascular system, consisting of the heart and blood vessels, ensures delivery of oxygen and nutrient-rich blood throughout the whole body. The major cell types include cardiomyocytes, endothelial cells, and vascular smooth muscle cells. Dramatic
Mireia Nàger +3 more
doaj +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
npj Digital MedicineEstablishing whether observed behavioral differences reflect meaningful change in an individual necessitates baselines specific to the individual and task. Automated hybrid solutions combine adaptive baselines with fixed thresholds.
Sandra Anna Just +6 more
doaj +1 more source