Results 121 to 130 of about 299,530 (310)

Effectiveness of Corticosteroid Strategy in Three Community‐Acquired Pneumonia Clinical Phenotypes: A Multicenter Retrospective Cohort Study

open access: yesMed Research, EarlyView.
ABSTRACT Comprehensive understanding of community‐acquired pneumonia (CAP) patient's clinical phenotypes is imperative for facilitating prognosis and formulating treatment guidelines. However, the efficacy of corticosteroid therapy in managing CAP remains a topic of debate requiring further scrutiny.
Qiangqiang Qin   +12 more
wiley   +1 more source

Complexity and unanswered questions in the pathophysiology of COVID-19 ARDS [PDF]

open access: bronze, 2021
Davide Chiumello   +3 more
openalex   +1 more source

The Nutrigenomic Effect of Mela Rosa Marchigiana Callus Extract on Cellular Senescence: Insight From a Preliminary In Vitro Study

open access: yesMolecular Nutrition &Food Research, EarlyView.
Mela Rosa Marchigiana (MRM) is an ancient apple variety peculiar of the center of Italy. The in vitro culture of the MRM pulp explants leaded to the production of calluses whose ethanolic extract has been suggested to be rich in pentacyclic triterpenic acids.
Chiara Rucci   +16 more
wiley   +1 more source

Effective and Safe Use of Glucocorticosteroids for Rescue of Late ARDS [PDF]

open access: gold, 2017
Paolo Diana   +3 more
openalex   +1 more source

Mesenchymal stem cells inhibited the apoptosis of alveolar epithelial cells caused by ARDS through CXCL12/CXCR4 axis

open access: gold, 2022
Xiqiang He   +7 more
openalex   +1 more source

Systematic Parameter Selection for Short Fiber Polymer Composite Direct Fiber Simulation

open access: yesPolymer Composites, EarlyView.
Interactions of individually simulated fibers are systematically calibrated such that their orientation history agrees with the results from analytical orientation models. ABSTRACT The orientation of fibers in short discontinuous fiber reinforced polymer composites is a critical factor in determining final mechanical and thermal properties.
Jason B. Pierce, Douglas E. Smith
wiley   +1 more source

Glucocorticoid‐Induced TNFR‐Related Ligand as a Biomarker for Diagnosis and Severity of Asthma in Children

open access: yesPediatric Discovery, EarlyView.
Our study demonstrates elevated GITRL expression in HDM‐exposed dendritic cells (in vitro), murine asthma models, and pediatric asthma patients, and reveals a direct association between GITRL levels and disease severity in children. ABSTRACT Currently, there are no reliable pediatric biomarkers for assessing the severity of asthma. Therefore, the study
Yuehan Li   +7 more
wiley   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said   +10 more
wiley   +1 more source

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