Results 121 to 130 of about 287,804 (304)

Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He, Nan Su, Yuqing Wang, Yulin Sun, Xin Weng, Tania Pereira, Chenggong Hu, Keliang Xie, Meijun Pang, Kuo Zhang, Chuanxiang Huang, Xiuyun Liu   +11 more
wiley   +1 more source

Rumen methanogenic archaea and their correlation with enteric methane emission in ruminant animals: A systematic review and meta‐analysis

JSFA reports, EarlyView.
Abstract Background Livestock, especially ruminants, are a major source of global methane emissions, primarily produced by methanogenic archaea during enteric fermentation. We performed a systematic review and meta‐analysis to account for factors that could influence the relationship between ruminal methanogenic populations and methane emissions, such ...
Arlan Araujo Rodrigues, Igor Machado Ferreira, Fiorella Viquez Umana, Juliana Silva de Oliveira, Hilario C. Mantovani   +4 more
wiley   +1 more source

Deresuscitation Informed by Ultrasound in Patients with Septic Shock Trial

Journal of Ultrasound in Medicine, EarlyView.
Objectives The venous excess ultrasound (VExUS) can be used at the point‐of‐care to identify venous overload and end‐organ congestion in an effort to individually tailor resuscitation and deresuscitation in patients with septic shock. Methods We conducted a pilot randomized controlled feasibility trial of VExUS‐guided fluid management in adult patients
Brendan Innes, Christopher Allison, Nicholas Seidler, Burton Shen, Andrew Fried, Gary Phillips, Andrew Levinson, Adeel Abbasi   +7 more
wiley   +1 more source

LncRNA NORAD Enhances Inflammatory Injury in Sepsis‐Associated Acute Lung Damage Through miR‐150‐5p/STAT1‐Dependent NF‐κB Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu, Xi‐Xi Chen, Gui‐Hua Wei, Feng Li, Hai‐Yan Zong   +4 more
wiley   +1 more source

Biopolymers and acute respiratory distress syndrome associated with administration of biopolymers, a path to perfection or death: A Case report

Journal of Mechanical Ventilation
Biopolymers are synthetic macromolecules that can cause multiple complications, both local and systemic, which can manifest immediately or years later. Complications of biopolymer administration are increasingly common.
Sergio G Monasterios-López, Martín A Ríos-Ayala, Carmen Hernández-Cárdenas, Gustavo Lugo-Goytia, Jaritzy G Lagunez Caramón   +4 more
doaj   +1 more source

Robotic‐Assisted Electrode Array Insertion Improves Stability of Acoustic Hearing Thresholds

The Laryngoscope, EarlyView.
This study evaluated the impact of robotic‐assisted electrode array insertion on rates of delayed‐onset hearing loss (DOHL). DOHL occurred in 22 of 60 subjects (37%) in the manual cohort compared with 2 of 29 subjects (7%) in the robotic‐assisted cohort, representing a statistically significant reduction (p = 0.002).
Uzair A. Khan, Rachel A. Scheperle, Grant Podhajsky, Meggan J. Lind, Camille C. Dunn, Alexander D. Claussen, Bruce J. Gantz, Marlan R. Hansen   +7 more
wiley   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

Offline Reconstruction of Diffusion MRI Acquisitions for Comparison Between Complex PCA‐Based and AI‐Based Denoising

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Optimal diffusion MRI (dMRI) data for image denoising is often unavailable from scanner reconstruction. In this work, we make available an offline reconstruction pipeline for GE dMRI acquisitions, giving access to complex dMRI data. Furthermore, we compare the efficacy of GE HealthCare's AIR‐Recon DL (ARDL), a proprietary convolutional
Francesco D'Antonio, Shaun Warrington, Jose‐Pedro Manzano‐Patron, Paul S. Morgan, Stamatios N. Sotiropoulos   +4 more
wiley   +1 more source

Improvement in radiologic findings over time is associated with increased survival in patients with viral ARDS requiring extracorporeal membrane oxygenation

Lung India
Introduction: Acute respiratory distress syndrome (ARDS) requiring venovenous extracorporeal membrane oxygenation (VV ECMO) support is associated with chest radiograph changes commonly referred to as “drowning ECMO lung” ECMO lung presents as white-out ...
Laura DiChiacchio, Ikeoluwapo Ibrahim, Alison Grazioli, Neda Bionghi, Kiran Batra, Sameer Chabbra, Nicholas Ladikos, Vaidehi Kaza, Srinivas Bollineni, Manish R. Mohanka, Adrian Lawrence, Fernando Torres, Aldo Iacono, Daniel Herr, Irina Timofte   +14 more
doaj   +1 more source

Twenty‐Four Month Outcomes From a Real‐World Telehealth Obesity Treatment Clinic Using Obesity Medications

Obesity, EarlyView.
ABSTRACT Objective Antiobesity medications (AOMs) are indicated for long‐term use; however, evidence of their real‐world long‐term efficacy is limited. This study describes clinical outcomes from 18‐ and 24‐month use of AOMs in a telemedicine weight management clinic.
Kathleen R. Ruddiman, Young‐Rock Hong, Jamy Ard, Rebecca Jones, Adam Medcalf, Gary D. Foster, Jamil Alkhaddo, Michelle Cardel   +7 more
wiley   +1 more source