Results 101 to 110 of about 117,203 (308)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu +4 more
wiley +1 more source
Dexamethasone for treatment of severe COVID-19, a surprise?
The Cardiothoracic Surgeon, 2020 Hany Hasan Elsayed
doaj +1 more source
Infection and Drug ResistanceXuyan Li,1 Lujia Guan,1 Dong Wang,1 Xiao Tang,1 Rui Wang,1 Ying Li,1 Zhaohui Tong,1 Bing Sun,1 Chen Wang2– 5 1Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical ...
Li X +8 more
doaj
Exploring the lung-gut direction of the gut-lung axis in patients with ARDS. [PDF]
Acute respiratory distress syndrome (ARDS) represents a life-threatening inflammatory reaction marked by refractory hypoxaemia and pulmonary oedema. Despite advancements in treatment perspectives, ARDS still carries a high mortality rate, often due to ...
Ziaka, Mairi, Exadaktylos, Aristomenis
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The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang +4 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said +10 more
wiley +1 more source
The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis
Phytotherapy Research, EarlyView.ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang +7 more
wiley +1 more source
Journal of Mechanical VentilationBiopolymers are synthetic macromolecules that can cause multiple complications, both local and systemic, which can manifest immediately or years later. Complications of biopolymer administration are increasingly common.
Sergio G Monasterios-López +4 more
doaj +1 more source