Results 91 to 100 of about 30,897 (254)

Targeting eEF1A1 With Baicalein to Block eEF1A1/Prdx4 Interaction for Treating Sepsis‐Mediated Lung Injury

Exploration, EarlyView.
Targeting eEF1A1 with baicalein disrupts the eEF1A1‐Prdx4 interaction to prevent RNF14‐mediated ubiquitination and degradation of Prdx4. This stabilizes Prdx4 to suppress NF‐κB, thereby alleviating sepsis‐induced acute lung injury. ABSTRACT Sepsis is a systemic inflammatory response syndrome triggered by an uncontrolled host response to infection ...
Jing Chang, Hui‐Lin Zhang, Qi‐Meng Zhu, Si‐Wen Hui, Xin‐Rong Xu, Mahmood Brobbey Oppong, Yan‐Li Feng, Juan Zhang, Cheng‐Peng Sun, Feng Qiu   +9 more
wiley   +1 more source

Evaluation of the Effects of Baricitinib and Ruxolitinib in Acute Respiratory Distress Syndrome (ARDS) Patients: A Meta-Analysis Study [PDF]

Pharmaceutical Sciences
Background: Acute respiratory distress syndrome (ARDS) is a severe lung disease with a high rate of morbidity and mortality. Baricitinib and Ruxolitinib, known as Janus kinase (JAK) inhibitors, have shown promise in mitigating the inflammatory response ...
Mehdi Nurmohammad Ahari, Ata Mahmoodpoor, Hassan Soleimanpour, Hamed Valizadeh, Shadi Ziaie, Hadi Hamishehkar   +5 more
doaj   +1 more source

Dynamic Immune Indicator Changes as Predictors of ARDS in ICU Patients with Sepsis: A Retrospective Study [PDF]

Xiaochi Lu,1 Yi Chen,1 Gongping Zhang,1 Xu Zeng,1 Linjie Lai,1 Chaojun Qu2 1Department of Emergency Medicine, Lishui Municipal Central Hospital, Lishui, 323000, People’s Republic of China; 2Department of Intensive Care Unit, Lishui Municipal Central ...
Zhang G, Qu C, Lu X, Chen Y, Zeng X, Lai L   +5 more
core  

Rapidly improving ARDS differs clinically and biologically from persistent ARDS. [PDF]

BACKGROUND: Rapidly improving acute respiratory distress syndrome (RIARDS) is an increasingly appreciated subgroup of ARDS in which hypoxemia improves within 24 h after initiation of mechanical ventilation.
Jones, Chayse, Wu, Nelson E, Matthay, Michael, Willmore, Andrew, Langelier, Charles R, Delucchi, Kevin L, Calfee, Carolyn S, Sinha, Pratik, Hendrickson, Carolyn M, Zhuo, Hanjing, Gomez, Antonio D, Hendrickson, Carolyn, Kangelaris, Kirsten N, Gomez, Antonio, Matthay, Michael A, Leligdowicz, Aleksandra, Neyton, Lucile, Kangelaris, Kirsten, Langelier, Charles, Liu, Kathleen, Neyton, Lucile P A, Liu, Kathleen D, Valda Toro, Patricia L, Sarma, Aartik, Calfee, Carolyn, Wu, Nelson, Delucchi, Kevin, Valda Toro, Patricia, Jauregui, Alejandra   +28 more
core   +1 more source

Time-controlled adaptive ventilation in patients with ARDS—lack of protocol adherence: a systematic review

Critical Care, 2023
Stephan Katzenschlager, Christoph M. Simon, Patrick Rehn, Maurizio Grilli, Mascha O. Fiedler, Michael Müller, Markus A. Weigand, Benjamin Neetz   +7 more
doaj   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

ARDS OF DIFFERENT ORIGIN: PSYCHOLOGICAL CONSEQUENCES IN THE POST DISMISSION

, 2022
non
MAISTO, ANGELICA
core  

Dexamethasone for treatment of severe COVID-19, a surprise?

The Cardiothoracic Surgeon, 2020
Hany Hasan Elsayed
doaj   +1 more source

National trends in pathogen‐specific diagnoses and outcomes among hospitalizations for infectious diarrhea

Journal of Hospital Medicine, EarlyView.
Abstract Background The diagnostic evaluation of infectious diarrhea has evolved with increasing adoption of multiplex gastrointestinal nucleic acid amplification tests and changing diagnostic strategies for Clostridioides difficile. Objectives We aimed to assess changes in inpatient pathogen‐specific documentation rates and clinical outcomes on a ...
David Wong Arias, Spencer R. Goble, Mauricio Torrealba   +2 more
wiley   +1 more source

Comparative Dosing of Adjunctive Corticosteroids Therapy for Pneumocystis Pneumonia with ARDS in Non-HIV Immunocompromised Patients

Infection and Drug Resistance
Xuyan Li,1 Lujia Guan,1 Dong Wang,1 Xiao Tang,1 Rui Wang,1 Ying Li,1 Zhaohui Tong,1 Bing Sun,1 Chen Wang2– 5 1Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical ...
Li X, Guan L, Wang D, Tang X, Wang R, Li Y, Tong Z, Sun B, Wang C   +8 more
doaj