Results 71 to 80 of about 30,897 (254)

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source

Preoperative FIB‐4 Index as a Potential Factor Associated With Severe Postoperative Complications and Endogenous Organ Failure After Hepatectomy for Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrates that a preoperative FIB‐4 index ≥ 5.0 independently predicts severe complications and endogenous organ failure (EOF) following hepatectomy for hepatocellular carcinoma. By capturing structural liver fragility and systemic vulnerability, the FIB‐4 index enhances surgical risk stratification beyond traditional functional markers ...
Masanori Nakamura, Yukiyasu Okamura, Osamu Aramaki, Nao Yoshida, Yusuke Mitsuka, Hayato Abe, Shunsuke Yamagishi, Yasuhiro Okumura, Kyongsun Pak, Shinobu Masuda   +9 more
wiley   +1 more source

Baseline characteristics of ARDS patients stratified by ARDS severity.

, 2016
Baseline characteristics of ARDS patients stratified by ARDS severity.
Lynn M. Schnapp (386799), Kristina Crothers (299662), W. Conrad Liles (63268), Engi F. Attia (2502751), Sarah E. Jolley (2502748)   +4 more
core   +1 more source

Integrating Reinforcement Learning With Explainable Artificial Intelligence for Real‐Time Clinical Decision Support in Dynamic Healthcare Environments

Advanced Intelligent Systems, EarlyView.
A hybrid Reinforcement Learning–Explainable AI framework integrates SHAP and LIME explanations directly into a Deep Q‐Network inference loop for real‐time ICU decision support. Trained on 18 142 mechanically ventilated stays from the eICU database, the system attains 93.0% decision accuracy, 20% fewer errors than RL alone, and a 91% clinician trust ...
Jannatul Ferdaus Disha, MD Faiaz Zaman Dehan, Kazi Md. Tanvir Anzum   +2 more
wiley   +1 more source

Prone Positioning: A Comparison Between COVID-19 ARDS and non-COVID-19 ARDS [PDF]

, 2021
Background: Coronavirus disease 2019 (COVID-19) is a viral respiratory disease caused by SARS-CoV-2. Critical cases evolve into an acute respiratory distress syndrome (ARDS) with bilateral infiltrates, intrapulmonary shunting, and hypoxemia requiring ...
Shin, Albert J
core   +1 more source

Predicting ICU Mortality in Acute Respiratory Distress Syndrome Patients Using Machine Learning: The Predicting Outcome and STratifiCation of severity in ARDS (POSTCARDS) Study

Objectives: To assess the value of machine learning approaches in the development of a multivariable model for early prediction of ICU death in patients with acute respiratory distress syndrome (ARDS).
Slutsky, Arthur, Villar, Jesús, ARDS (POSTCARDS) Network   +2 more
core   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source

Prognostic value of surfactant protein D and biochemical markers in BALF and plasma of ARDS patients undergoing mechanical ventilation [PDF]

Journal of Medical Biochemistry
Background: Surfactant protein D (SP-D) and circulating exosomes have emerged as potential biochemical indicators of lung injury severity in acute respiratory distress syndrome (ARDS).
Han Hu, Zhang Litao, Shen Zhangshun, Hua Ranliang, Li Lingling, Guo Hui   +5 more
doaj   +1 more source

Early evolution of the gular musculature and its innervation in ray‐finned fishes

The Anatomical Record, EarlyView.
Abstract Gular muscles are an important but often overlooked component of cranial anatomy in bony fishes. They are located on the ventral surface of the head and are derived from the mandibular and hyoid arches. We present a comprehensive review of the gular musculature and its innervation across early diverging actinopterygian lineages. By integrating
Aléssio Datovo, Paulo Presti, George Vita, Murilo N. L. Pastana, Luiz A. W. Peixoto   +4 more
wiley   +1 more source

Tracing the evolutionary history of the morpho‐anatomy of baculum in primates

The Anatomical Record, EarlyView.
Abstract Animal morphology reflects both evolutionary history and present‐day adaptation. Male mammal copulatory structures such as the baculum (penile bone) are ideal for studying these processes because of their complexity and high interspecific variability. In primates, however, research has focused mostly on baculum length.
Federica Spani, Maria Pia Morigi, Matteo Bettuzzi, Monica Carosi   +3 more
wiley   +1 more source