Results 51 to 60 of about 30,897 (254)

Metabolic signatures of ARDS and ARDS heterogeneity [PDF]

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2021
Lucile Neyton, Carolyn S. Calfee
openaire   +2 more sources

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

Acute Pancreatitis and COVID-19: A Single-Center Experience

Journal of Multidisciplinary Healthcare, 2021
Anna Annunziata,1 Antonietta Coppola,1 Paolo Andreozzi,2 Maurizia Lanza,1 Francesca Simioli,1 Novella Carannante,3 Camilla Di Somma,1 Pierpaolo Di Micco,4 Giuseppe Fiorentino1 1Department of Critic Area, I Unit COVID, Monaldi-Cotugno Hospital, Naples ...
Annunziata A, Coppola A, Andreozzi P, Lanza M, Simioli F, Carannante N, Di Somma C, Di Micco P, Fiorentino G   +8 more
doaj  

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

‘The Contrast May Burn a Little' - Case Report of Severe, Anaphylactic Shock Following MRI IV Contrast

Saudi Journal of Emergency Medicine
We present a case of a 46-year-old male who developed acute onset shortness of breath, hypotension, and hypoxia soon after receiving IV contrast for a routine MRI scan.
Elrasheed Salih, Mohammed Anzal Rehman, Rishi Prasad   +2 more
doaj   +1 more source

Simvastatin to reduce pulmonary dysfunction in patients with acute respiratory distress syndrome: the HARP-2 RCT

Efficacy and Mechanism Evaluation, 2018
Background: Acute lung injury is a common devastating clinical syndrome characterised by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure, and is a major cause of morbidity and mortality.
Daniel F McAuley, John G Laffey, Cecilia M O’Kane, Gavin D Perkins, Brian Mullan, Thomas J Trinder, Paul Johnston, Phillip A Hopkins, Andrew J Johnston, Lynn Murphy, Christine McNally, Ashley M Agus, Clíona McDowell, Colette Jackson   +13 more
doaj   +1 more source

Quantification of atelectatic lung volumes in two different porcine models of ARDS [PDF]

, 2006
BACKGROUND: Cyclic recruitment during mechanical ventilation contributes to ventilator associated lung injury. Two different pathomechanisms in acute respiratory distress syndrome (ARDS) are currently discussed: alveolar collapse vs persistent flooding ...
Heussel, C-P, Yuan, S., Heussel, C.-P., Karmrodt, J., Bletz, C., David, M, Markstaller, K, David, M., Karmrodt, J, Bletz, C, Markstaller, Klaus, Yuan, S   +11 more
core   +2 more sources

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Comparing lung mechanics of patients with COVID related respiratory distress syndrome versus non-COVID acute respiratory distress syndrome: a retrospective observational study

Journal of Mechanical Ventilation, 2022
Background Most patients admitted to the intensive care unit with coronavirus disease (COVID-19) develop severe respiratory failure. Understanding lung mechanics helps to guide protective mechanical ventilation, improve oxygenation, and reduce the ...
Francisco Chacón-Lozsán, Péter Tamási   +1 more
doaj   +1 more source

Acute Respiratory Distress Syndrome (ARDS) After Nitric Acid Inhalation

, 2014
Lung injury resulting from inhalation of chemical products continues to be associated with high morbidity and mortality. Concentrated nitric acids are also extremely corrosive fuming chemical liquids.
Gizem Avcı, Bektaş Akpolat, Gülay Kır, Leyla Veral   +3 more
core   +1 more source