Results 61 to 70 of about 117,311 (310)

Acute Pancreatitis and COVID-19: A Single-Center Experience

open access: yesJournal of Multidisciplinary Healthcare, 2021
Anna Annunziata,1 Antonietta Coppola,1 Paolo Andreozzi,2 Maurizia Lanza,1 Francesca Simioli,1 Novella Carannante,3 Camilla Di Somma,1 Pierpaolo Di Micco,4 Giuseppe Fiorentino1 1Department of Critic Area, I Unit COVID, Monaldi-Cotugno Hospital, Naples ...
Annunziata A   +8 more
doaj  

Lonicera japonica‐Derived Nanovesicles Ameliorate Acute Lung Injury by Suppressing Neutrophil Extracellular Traps Formation in Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
(A) Isolation and purification of LDNVs. (B) Establishment of the ALI model and LDNVs delivery. (C) Therapeutic mechanisms of LDNVs in treating ALI. This scheme figure was drawn by Figdraw, ID: IUIIO21222. ABSTRACT Acute lung injury (ALI) is a lethal respiratory disease.
Xi Lin   +10 more
wiley   +1 more source

‘The Contrast May Burn a Little' - Case Report of Severe, Anaphylactic Shock Following MRI IV Contrast

open access: yesSaudi Journal of Emergency Medicine
We present a case of a 46-year-old male who developed acute onset shortness of breath, hypotension, and hypoxia soon after receiving IV contrast for a routine MRI scan.
Elrasheed Salih   +2 more
doaj   +1 more source

Simvastatin to reduce pulmonary dysfunction in patients with acute respiratory distress syndrome: the HARP-2 RCT

open access: yesEfficacy and Mechanism Evaluation, 2018
Background: Acute lung injury is a common devastating clinical syndrome characterised by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure, and is a major cause of morbidity and mortality.
Daniel F McAuley   +13 more
doaj   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

open access: yesAdvanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray   +3 more
wiley   +1 more source

[Post-traumatic ARDS--a potential indication for lung transplantation?] [PDF]

open access: yes, 1993
Posttraumatic adult respiratory distress syndrome (ARDS) still involves significant mortality, despite progress in management concepts. Current therapeutic strategies are briefly described, including kinetic therapy, high-frequency jet ventilation and ...
Demertzis, S, Haverich, A
core  

Principles and Management of ARDS [PDF]

open access: yes, 2023
Acute respiratory distress syndrome (ARDS) was described for the first time more than 40 years ago. Since then, several progresses have been made in its definition, management, and in the understanding of the underlying pathophysiology. Despite ARDS is a
Pellegrini, Mariangela   +2 more
core   +1 more source

Comparing lung mechanics of patients with COVID related respiratory distress syndrome versus non-COVID acute respiratory distress syndrome: a retrospective observational study

open access: yesJournal of Mechanical Ventilation, 2022
Background Most patients admitted to the intensive care unit with coronavirus disease (COVID-19) develop severe respiratory failure. Understanding lung mechanics helps to guide protective mechanical ventilation, improve oxygenation, and reduce the ...
Francisco Chacón-Lozsán   +1 more
doaj   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

open access: yesAdvanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding   +13 more
wiley   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

open access: yesAdvanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou   +11 more
wiley   +1 more source

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