Results 81 to 90 of about 117,203 (308)

Inhalation surfactant therapy in the integrated treatment of severe COVID-19 pneumonia

Туберкулез и болезни лёгких, 2020
The objective: to evaluate the effectiveness of inhaled surfactant therapy in the integrated treatment of severe COVID-19 pneumonia in a multicenter prospective clinical trial of surfactant-BL.Subjects and methods.
A. E. Bautin, S. N. Avdeev, A. A. Seyliev, M. V. Shvechkova, Z. M. Merzhoeva, N. V. Trushenko, A. P. Semenov, K. B. Lapshin, O. A. Rozenberg   +8 more
doaj   +1 more source

SUDEP and mortality in developmental and epileptic encephalopathies: A meta‐analysis of randomized clinical trials and extension studies

Epilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are associated with high premature mortality and increased risk of sudden unexpected death in epilepsy (SUDEP). However, epidemiological data remain limited, particularly for specific syndromes such as Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), and infantile epileptic ...
Pierludovico Moro, Maria Sole Borioni, Adolfo Mazzeo, Enrico Cocchi, Carlo Di Bonaventura, Emanuele Cerulli Irelli   +5 more
wiley   +1 more source

Sixty-Day Mortality Among 520 Italian Hospitalized COVID-19 Patients According to the Adopted Ventilatory Strategy in the Context of an Integrated Multidisciplinary Clinical Organization: A Population-Based Cohort Study

Clinical Epidemiology, 2020
Antonella Potalivo,1,* Jonathan Montomoli,1,* Francesca Facondini,1 Gianfranco Sanson,2 Luigi Arcangelo Lazzari Agli,3,4 Tiziana Perin,5 Francesco Cristini,6 Enrico Cavagna,7 Raffaella De Giovanni,8 Carlo Biagetti,6 Ilaria Panzini,9 Cinzia Ravaioli,10 ...
Potalivo A, Montomoli J, Facondini F, Sanson G, Lazzari Agli LA, Perin T, Cristini F, Cavagna E, De Giovanni R, Biagetti C, Panzini I, Ravaioli C, Bitondo MM, Guerra D, Giuliani G, Mosconi E, Guarino S, Marchionni E, Gangitano G, Valentini I, Giampaolo L, Muratore F, Nardi G   +22 more
doaj  

Beta Agonist Lung Injury TrIal-2 (BALTI-2) trial protocol : a randomised, double-blind, placebo-controlled of intravenous infusion of salbutamol in the acute respiratory distress syndrome [PDF]

, 2011
Background: The Acute Respiratory Distress Syndrome (ARDS) is a common cause of respiratory failure in critically ill patients. Experimental studies suggest that treatment with beta agonists may be helpful in ARDS.
McCabe Chris, Young Duncan, Lamb, Sarah E, Young, Duncan S., McCabe, Chris, Gao, F, Perkins, Gavin D., Gates, S, Smith, F. Gao, Lamb, S. E., Chris McCabe, Fang Gao, Young, D, Duncan Young, Gao, Fang; id_orcid, Gao Fang, Perkins, GD, Young, Duncan, Gates, Simon, Lamb, Sarah, Sarah E Lamb, Gavin D Perkins, Perkins, Gavin D, Simon Gates, Lamb Sarah E, Gates Simon, McCabe, C, Perkins Gavin D, Lamb, SE   +28 more
core   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Rapidly improving ARDS differs clinically and biologically from persistent ARDS. [PDF]

BACKGROUND: Rapidly improving acute respiratory distress syndrome (RIARDS) is an increasingly appreciated subgroup of ARDS in which hypoxemia improves within 24 h after initiation of mechanical ventilation.
Jones, Chayse, Wu, Nelson E, Matthay, Michael, Willmore, Andrew, Langelier, Charles R, Delucchi, Kevin L, Calfee, Carolyn S, Sinha, Pratik, Hendrickson, Carolyn M, Zhuo, Hanjing, Gomez, Antonio D, Hendrickson, Carolyn, Kangelaris, Kirsten N, Gomez, Antonio, Matthay, Michael A, Leligdowicz, Aleksandra, Neyton, Lucile, Kangelaris, Kirsten, Langelier, Charles, Liu, Kathleen, Neyton, Lucile P A, Liu, Kathleen D, Valda Toro, Patricia L, Sarma, Aartik, Calfee, Carolyn, Wu, Nelson, Delucchi, Kevin, Valda Toro, Patricia, Jauregui, Alejandra   +28 more
core   +1 more source

[Post-traumatic ARDS--a potential indication for lung transplantation?]

, 1993
Posttraumatic adult respiratory distress syndrome (ARDS) still involves significant mortality, despite progress in management concepts. Current therapeutic strategies are briefly described, including kinetic therapy, high-frequency jet ventilation and ...
Demertzis, S, Haverich, A
core  

Principles and Management of ARDS

, 2023
Acute respiratory distress syndrome (ARDS) was described for the first time more than 40 years ago. Since then, several progresses have been made in its definition, management, and in the understanding of the underlying pathophysiology. Despite ARDS is a
Pellegrini, Mariangela, Scaramuzzo, Gaetano, Borgstedt, Laura   +2 more
core   +1 more source

Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He, Nan Su, Yuqing Wang, Yulin Sun, Xin Weng, Tania Pereira, Chenggong Hu, Keliang Xie, Meijun Pang, Kuo Zhang, Chuanxiang Huang, Xiuyun Liu   +11 more
wiley   +1 more source

Evaluation of the Effects of Baricitinib and Ruxolitinib in Acute Respiratory Distress Syndrome (ARDS) Patients: A Meta-Analysis Study [PDF]

Pharmaceutical Sciences
Background: Acute respiratory distress syndrome (ARDS) is a severe lung disease with a high rate of morbidity and mortality. Baricitinib and Ruxolitinib, known as Janus kinase (JAK) inhibitors, have shown promise in mitigating the inflammatory response ...
Mehdi Nurmohammad Ahari, Ata Mahmoodpoor, Hassan Soleimanpour, Hamed Valizadeh, Shadi Ziaie, Hadi Hamishehkar   +5 more
doaj   +1 more source