Results 151 to 160 of about 299,530 (310)

Age‐Dependent KLK8 Upregulation Contributes to Elevated Susceptibility to Ventilator‐Induced Lung Injury in the Elderly Mice

open access: yesAging Cell, EarlyView.
Our research firstly indicated that age‐dependent upregulation of tissue kallikrein‐related peptidase 8 (KLK8) induces endothelial senescence through modulating the fibronectin‐FAK‐Akt‐PARP1/2 axis, thereby increasing the vulnerability of aged mice to low‐tidal‐volume ventilator‐induced lung injury (VILI).
Di Liu   +7 more
wiley   +1 more source

Increased serum levels of procollagen type III peptide in severely injured patients [PDF]

open access: yes, 1993
Objectives: To determine the serum concentrations of procollagen type in peptide in severely injured patients with different outcomes and to evaluate the relationship between serum procollagen type III peptide concentrations, sources of increased ...
Duswald, Karl-Heimo   +6 more
core  

Adaptive radial-based direction sampling; Some flexible and robust Monte Carlo integration methods [PDF]

open access: yes
Adaptive radial-based direction sampling (ARDS) algorithms are specified for Bayesian analysis of models with nonelliptical, possibly, multimodal target distributions.A key step is a radial-based transformation to directions and distances.
Bauwens, L.   +3 more
core   +1 more source

Severe Patients With ARDS With COVID-19 Treated With Extracorporeal Membrane Oxygenation in China: A Retrospective Study [PDF]

open access: gold, 2021
Lai Wei   +8 more
openalex   +1 more source

Social cognition in Korsakoff's syndrome: A meta‐analysis

open access: yesAddiction, EarlyView.
Abstract Background and aims Korsakoff's syndrome is an alcohol‐related neurocognitive disorder characterized by episodic memory impairments, apathy, confabulations and poor illness‐insight. This meta‐analysis aimed to estimate mean effect sizes of performance in social cognition in people with Korsakoff's syndrome (KS) compared with controls. Method A
Kyra Wijnen   +4 more
wiley   +1 more source

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma

open access: yesAllergy, EarlyView.
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong   +217 more
wiley   +1 more source

Immune Training of the Interleukin 6 Gene in Airway Epithelial Cells is Central to Asthma Exacerbations

open access: yesAllergy, EarlyView.
This study aims to investigate how immune activation influences the epigenetic regulation and expression of the Interleukin‐6 (IL‐6) gene during asthma exacerbations. By examining molecular mechanisms of immune training, we seek to elucidate how IL‐6‐driven inflammatory pathways contribute to airway dysfunction and worsening asthma symptoms.
Lars P. Lunding   +34 more
wiley   +1 more source

High Induction of IL-6 Secretion From hUCMSCs Optimize the Potential of hUCMSCs and TCZ as Therapy for COVID-19-Related ARDS

open access: gold, 2021
Huei-Yu Lo   +9 more
openalex   +1 more source

Prognostic factors for ARDS: clinical, physiological and atypical immunodeficiency [PDF]

open access: green, 2020
Min Sup Song   +5 more
openalex   +1 more source

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