Results 171 to 180 of about 99,596 (264)

Comparative Effectiveness Analysis of Phase 3 Clinical Trials in Moderately to Severely Active Inflammatory Bowel Disease Reveals Increased Harm From Placebo and Challenges Equipoise

open access: yesJCC Plus, Volume 1, Issue 5, September 2026.
Across 47 Phase 3 trials in Crohn's disease and ulcerative colitis, placebo exposure was associated with measurable harm. Disease exacerbation events showed the greatest excess risk, with one additional exacerbation occurring for every 8–13 patients assigned to placebo rather than active therapy.
Joëlle St‐Pierre   +5 more
wiley   +1 more source

Relevant insights from personalized inhaled carbon monoxide dosing in a safety study in pneumonia and ARDS. [PDF]

open access: yesRespir Res
Baron RM   +9 more
europepmc   +1 more source

Early prediction of multiple organ failure for sepsis patients based on machine learning algorithms

open access: yesJournal of Intelligent Medicine, Volume 3, Issue 3, Page 277-289, September 2026.
Abstract In recent years, there has been a notable rise in sepsis incidence leading to more multiple organ failure and higher mortality. The lack of effective treatments for sepsis highlights the importance of early prediction in preventing multiple organ failure. This study aimed to develop a model for the early prediction of multiple organ failure in
Runnan He   +11 more
wiley   +1 more source

Prostate Cancer Development, Progression, and Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin   +9 more
wiley   +1 more source

Stress-hyperglycemia ratio and glycemic variability predict severity and mortality in sepsis-associated acute respiratory distress syndrome. [PDF]

open access: yesWorld J Emerg Med
Chen H   +14 more
europepmc   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

open access: yes
Transfusion, EarlyView.
Thane Kubik   +2 more
wiley   +1 more source

Characterizing How Community‐Level Plant Functional Traits Impact Soil Microbial Diversity

open access: yesJournal of Sustainable Agriculture and Environment, Volume 5, Issue 3, September 2026.
ABSTRACT Introduction Functional trait‐based approaches have been suggested for designing functionally diverse plant communities to influence soil microbial community structure and diversity. However, it remains unclear how species‐level plant functional traits (PFTs) and microbial associations translate to community‐level functional trait and soil ...
Prashasti Agarwal   +4 more
wiley   +1 more source

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