Results 101 to 110 of about 19,311,004 (300)

Productivity versus area: The growth dilemma of the Uruguayan dairy sector

open access: yesAgrociencia Uruguay
The objective of this study was to analyze the development dynamic of the Uruguayan dairy farms in the last decade integrating country, experimental and commercial databases. A large commercial dairy farm database was segmented into four groups according
Pablo Chilibroste   +2 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

10th November (1.14 MB) [PDF]

open access: yes, 2000
NAHB ...
Northern Area Health Board (NAHB)
core  

Drawing Graphs within Restricted Area

open access: yes, 2014
We study the problem of selecting a maximum-weight subgraph of a given graph such that the subgraph can be drawn within a prescribed drawing area subject to given non-uniform vertex sizes.
C.A. Duncan   +14 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Diseño de una aplicación de realidad virtual para entrenamiento cognitivo de pacientes con Alzheimer [PDF]

open access: yes, 2018
Avui en dia es cada vegada més comú veure animacions en 3D, ja pot ser per finalitats lúdiques o per finalitats educatives o professionals. En aquest projecte s’ha desenvolupat una aplicació en la que s’ha integrat l’animació 3D amb la realitat virtual ...
Ribas Riera, Óscar   +1 more
core  

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