Results 101 to 110 of about 11,092,458 (299)

Turkish Studies in China: Language, Academia and Multidisciplinary Perspectives

open access: yesŞarkiyat Mecmuası
This article provides a comprehensive examination of the historical evolution and interdisciplinary expansion of Turkish Studies in China. Türkiye’s strategic importance in the Belt and Road Initiative (BRI) has significantly intensified Chinese academic
Jiayi Zhu
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Financial incentives for return of service in underserved areas: a systematic review [PDF]

open access: yes
Of the 42 reviewed studies 33 investigated financial-incentive programs in the US. The remaining studies evaluated programs in Japan (five studies), Canada (two), New Zealand (one) and South Africa (one). The programs started between 1930 and 1998.
David E. Bloom, Till Barnighausen
core  

Studies of the effects of industrial pollution in the lower Patapsco river area: 1. Curtis Bay Region 1941 [PDF]

open access: yes, 1941
Industrial effluents in the lower Patapsco area, which constitutes the navigable portion of the river and includes Baltimore Harbor, are many and include waste acid, distillery waters, tannery wastes and copper as (ferrous sulphate) from pigment and ...
Brust, H.F.   +2 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Variabilità culturale nel XXI secolo e intersezione tra “Area studies” e Scienze Sociali per la produzione di nuova conoscenza

open access: yesCulture e Studi del Sociale, 2019
The present article investigates the new developments and challenges of social sciences and humanities in the era of globalization and underlines the importance of social sciences` intersection with interdisciplinary and transregional collaborative ...
Filomena Riccardi
doaj  

Interdyscyplinarność a zagrożenia strukturalne dla socjologii krytycznej. Artykuł dyskusyjny

open access: yesPrzeglad Socjologii Jakosciowej
W artykule przedstawiono pogląd na temat zagrożeń wynikających dla socjologii, w szczególności socjologii krytycznej, ze strukturalnych przemian w naukach społecznych, których legitymizacją jest coraz większe znacznie interdyscyplinarności. Jak wskazano,
Tomasz Zarycki
doaj   +1 more source

Seeing the wood for the trees: empire, nation-making and forest management [PDF]

open access: yes, 2008
Seemingly operating in an inverse relationship to the declining area of actual forest, the vast wood of publications on the topic continues to grow (thereby likely adding to the deforestation of the books’ subject).
Beattie, James John
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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